微/纳米塑料对哺乳动物消化道和呼吸道影响研究进展
Progress on Effects of Micro/Nanoplastics on Digestive Tract and Respiratory Tract of Mammals
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摘要: 塑料产品因其出色的功能在我们的日常生活中被广泛使用,但与此同时也产生了大量的塑料垃圾,这些塑料垃圾经多种途径分解成的微/纳米塑料广泛存在于环境中。微/纳米塑料通过食物、水和空气直接接触哺乳动物的消化道和呼吸道,引起哺乳动物消化道炎症反应、氧化应激、菌群失调和呼吸道细胞毒性,增加患慢性阻塞性肺病的风险以及与其吸附的其他有毒污染物联合作用对呼吸道产生的复合毒性等,危害人和动物健康。本文综述了微/纳米塑料对哺乳动物消化道和呼吸道的影响及其作用机制。Abstract: Plastics have many distinct properties and is nowadays widely used in daily life. Plastic breakdown in the environment leads to increasingly smaller fragments, called microplastic and nanoplastic. Exposure to micro/nano plastics in mammals can occur through inhalation or oral intake. Exposure to micro/nano plastics can impair digestive tract and respiratory tract of mammals, causing inflammation, oxidative stress, dysbacteriosis and respiratory cytotoxicity and chronic obstructive pulmonary disease, endanger human and animal health. We have reviewed the effects of micro/nanoplastics on the digestive tract and respiratory tract of mammals and the underlying mechanisms.
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Key words:
- micro/nano plastics /
- mammal /
- alimentary tract /
- respiratory tract
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Hirt N, Body-Malapel M. Immunotoxicity and intestinal effects of nano- and microplastics: A review of the literature [J]. Particle and Fibre Toxicology, 2020, 17(1): 57 李博昊, 赵永豪, 孙洪杰, 等. 常见微塑料对水中镉离子和铅离子的吸附: 吸附能力和吸附机制[J]. 生态毒理学报, 2023, 18(2): 356-365 Li B H, Zhao Y H, Sun H J, et al. Adsorption of typical microplastics towards Cd2+ and Pb2+ in water: Adsorption capacity and mechanism [J]. Asian Journal of Ecotoxicology, 2023, 18(2): 356-365 (in Chinese)
Vighi M, Bayo J, Fernández-Piñas F, et al. Micro and nano-plastics in the environment: Research priorities for the near future [J]. Reviews of Environmental Contamination and Toxicology, 2021, 257: 163-218 Forte M, Iachetta G, Tussellino M, et al. Polystyrene nanoparticles internalization in human gastric adenocarcinoma cells [J]. Toxicology in Vitro: An International Journal Published in Association with BIBRA, 2016, 31: 126-136 Banerjee A, Shelver W L. Micro- and nanoplastic induced cellular toxicity in mammals: A review [J]. Science of the Total Environment, 2021, 755: 142518 Prüst M, Meijer J, Westerink R H S. The plastic brain: Neurotoxicity of micro- and nanoplastics [J]. Particle and Fibre Toxicology, 2020, 17(1): 24 Salimi A, Alavehzadeh A, Ramezani M, et al. Differences in sensitivity of human lymphocytes and fish lymphocytes to polyvinyl chloride microplastic toxicity [J]. Toxicology and Industrial Health, 2022, 38(2): 100-111 Li W X, Chen X F, Li M Q, et al. Microplastics as an aquatic pollutant affect gut microbiota within aquatic animals [J]. Journal of Hazardous Materials, 2022, 423(Pt B): 127094 Liang B X, Zhong Y Z, Huang Y J, et al. Underestimated health risks: Polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis [J]. Particle and Fibre Toxicology, 2021, 18(1): 20 Qiao R X, Deng Y F, Zhang S H, et al. Accumulation of different shapes of microplastics initiates intestinal injury and gut microbiota dysbiosis in the gut of zebrafish [J]. Chemosphere, 2019, 236: 124334 Jin Y X, Lu L, Tu W Q, et al. Impacts of polystyrene microplastic on the gut barrier, microbiota and metabolism of mice [J]. The Science of the Total Environment, 2019, 649: 308-317 Jin H B, Ma T, Sha X X, et al. Polystyrene microplastics induced male reproductive toxicity in mice [J]. Journal of Hazardous Materials, 2021, 401: 123430 Yong C Q Y, Valiyaveettil S, Tang B L. Toxicity of microplastics and nanoplastics in mammalian systems [J]. International Journal of Environmental Research and Public Health, 2020, 17(5): 1509 Li B Q, Ding Y F, Cheng X, et al. Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice [J]. Chemosphere, 2020, 244: 125492 Deng Y F, Yan Z H, Shen R Q, et al. Microplastics release phthalate esters and cause aggravated adverse effects in the mouse gut [J]. Environment International, 2020, 143: 105916 Jiang L, Schnabl B. Gut microbiota in liver disease: What do we know and what do we not know? [J]. Physiology, 2020, 35(4): 261-274 Mattioda V, Benedetti V, Tessarolo C, et al. Pro-inflammatory and cytotoxic effects of polystyrene microplastics on human and murine intestinal cell lines [J]. Biomolecules, 2023, 13(1): 140 Dong C D, Chen C W, Chen Y C, et al. Polystyrene microplastic particles: in vitro pulmonary toxicity assessment [J]. Journal of Hazardous Materials, 2020, 385: 121575 Wang C Y, Zhang Y, Deng M, et al. Bioaccumulation in the gut and liver causes gut barrier dysfunction and hepatic metabolism disorder in mice after exposure to low doses of OBS [J]. Environment International, 2019, 129: 279-290 Lu L, Luo T, Zhao Y, et al. Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health [J]. The Science of the Total Environment, 2019, 667: 94-100 Zhu X, Huang W, Fang M Z, et al. Airborne microplastic concentrations in five megacities of northern and southeast China [J]. Environmental Science & Technology, 2021, 55(19): 12871-12881 Lim S L, Ng C T, Zou L, et al. Targeted metabolomics reveals differential biological effects of nanoplastics andnanoZnO in human lung cells [J]. Nanotoxicology, 2019, 13(8): 1117-1132 Xu M K, Halimu G, Zhang Q R, et al. Internalization and toxicity: A preliminary study of effects of nanoplastic particles on human lung epithelial cell [J]. Science of the Total Environment, 2019, 694: 133794 Fournier S B, D’Errico J N, Adler D S, et al. Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy [J]. Particle and Fibre Toxicology, 2020, 17(1): 55 Li L Z, Xu Y, Li S X, et al. Molecular modeling of nanoplastic transformations in alveolar fluid and impacts on the lung surfactant film [J]. Journal of Hazardous Materials, 2022, 427: 127872 景美琪, 李绰然, 王隆清, 等. 微塑料的毒理学研究进展——微塑料对微生物、藻类、鱼类和哺乳动物类的毒理学效应[J]. 生态毒理学报, 2022, 17(4): 265-280 Jing M Q, Li C R, Wang L Q, et al. Toxicological research progress of microplastics: Toxicological effects of microplastics on microorganism, algae, fish and mammal [J]. Asian Journal of Ecotoxicology, 2022, 17(4): 265-280 (in Chinese)
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