溴系阻燃剂的毒理学研究进展

杜苗苗; 张娴; 颜昌宙

生态毒理学报

溴系阻燃剂的毒理学研究进展

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杜苗苗, 张娴, 颜昌宙. 溴系阻燃剂的毒理学研究进展[J]. 生态毒理学报, 2012, 7(6): 575-584.

引用本文:

杜苗苗, 张娴, 颜昌宙. 溴系阻燃剂的毒理学研究进展[J]. 生态毒理学报, 2012, 7(6): 575-584.

Du Miaomiao, Zhang Xian, Yan Changzhou. Advance in Researches on Toxicology of Brominated Flame Retardants[J]. Asian journal of ecotoxicology, 2012, 7(6): 575-584.

Citation:

Du Miaomiao, Zhang Xian, Yan Changzhou. Advance in Researches on Toxicology of Brominated Flame Retardants[J]. Asian journal of ecotoxicology, 2012, 7(6): 575-584.

溴系阻燃剂的毒理学研究进展

1. 中国科学院城市环境与健康重点实验室, 中国科学院城市环境研究所, 厦门 361021;
2. 中国科学院研究生院, 北京 100049

作者简介: 杜苗苗(1987-),女,硕士研究生,研究方向:环境科学;E-mail:mmdu@iue.ac.cn

基金项目:
中国科学院知识创新重要方向项目(KZCX2-YW-QN410)和国家自然科学基金项目(No．21007066)
中图分类号: X171.5

Advance in Researches on Toxicology of Brominated Flame Retardants

1. Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China;
2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China
Fund Project:

摘要: 溴系阻燃剂(brominated flame retardants,BFRs)广泛应用于塑料、电子、建筑、纺织等材料和产品中,在多种环境介质中都可以检测到BFRs的存在。目前市场上的溴系阻燃剂主要有3种:四溴双酚A (tetrabromobisphenol A,TBBPA)、多溴联苯醚(polybrominated diphenyl ethers,PBDEs)和六溴环十二烷(hexabromocyclododecanes,HBCDs)。近年来,进入环境中的BFRs在数量和种类上迅速增加,由此引发的环境效应日益受到国际社会广泛关注,有关BFRs的毒理学研究也成为相关领域的焦点内容。在总结近年来国内外相关研究的基础上,就BFRs在内分泌干扰效应、肝脏毒性、生殖毒性和神经毒性等方面的研究现状及需要进一步研究的内容进行了综述。
- 溴系阻燃剂 /
- 四溴双酚A /
- 多溴联苯醚 /
- 六溴环十二烷 /
- 毒理学
Abstract: Brominated flame retardants (BFRs) were widely used in plastics, electronics, buildings and textile materials, which were detected in various environmental matrices. Tetrabromobisphenol A (TBBPA), polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecanes (HBCDs) are main products of BFR on the market. In recent years, the types and quantities of BFRs into the environment have rapidly increased, the resulting environmental effects have been of great concern by international researches and toxicological studies on BFRs have become a hot issue in related fields. In this paper, the recent toxicological research of these three BFRs in endocrine-disrupting effect, hepatic toxicity, reproductive toxicity and neurotoxicity were summarized, the future research direction about their toxicity was discussed.
- brominated flame retardant /
- tetrabromobisphenol A /
- polybrominated diphenyl ether /
- hexabromocyclododecanes /
- toxicology

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杜苗苗, 张娴, 颜昌宙. 溴系阻燃剂的毒理学研究进展[J]. 生态毒理学报, 2012, 7(6): 575-584.

引用本文:

杜苗苗, 张娴, 颜昌宙. 溴系阻燃剂的毒理学研究进展[J]. 生态毒理学报, 2012, 7(6): 575-584.

Du Miaomiao, Zhang Xian, Yan Changzhou. Advance in Researches on Toxicology of Brominated Flame Retardants[J]. Asian journal of ecotoxicology, 2012, 7(6): 575-584.

Citation:

Du Miaomiao, Zhang Xian, Yan Changzhou. Advance in Researches on Toxicology of Brominated Flame Retardants[J]. Asian journal of ecotoxicology, 2012, 7(6): 575-584.

溴系阻燃剂的毒理学研究进展

作者简介: 杜苗苗(1987-),女,硕士研究生,研究方向:环境科学;E-mail:mmdu@iue.ac.cn
1. 中国科学院城市环境与健康重点实验室, 中国科学院城市环境研究所, 厦门 361021;

2. 中国科学院研究生院, 北京 100049

收稿日期: 2011-08-19

基金项目:

中国科学院知识创新重要方向项目(KZCX2-YW-QN410)和国家自然科学基金项目(No．21007066)

关键词:

摘要: 溴系阻燃剂(brominated flame retardants,BFRs)广泛应用于塑料、电子、建筑、纺织等材料和产品中,在多种环境介质中都可以检测到BFRs的存在。目前市场上的溴系阻燃剂主要有3种:四溴双酚A (tetrabromobisphenol A,TBBPA)、多溴联苯醚(polybrominated diphenyl ethers,PBDEs)和六溴环十二烷(hexabromocyclododecanes,HBCDs)。近年来,进入环境中的BFRs在数量和种类上迅速增加,由此引发的环境效应日益受到国际社会广泛关注,有关BFRs的毒理学研究也成为相关领域的焦点内容。在总结近年来国内外相关研究的基础上,就BFRs在内分泌干扰效应、肝脏毒性、生殖毒性和神经毒性等方面的研究现状及需要进一步研究的内容进行了综述。

English Abstract

Advance in Researches on Toxicology of Brominated Flame Retardants

1. Key Lab of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China;
2. Graduate University of Chinese Academy of Sciences, Beijing 100049, China

Received Date: 2011-08-19

Fund Project:

Keywords:

Abstract: Brominated flame retardants (BFRs) were widely used in plastics, electronics, buildings and textile materials, which were detected in various environmental matrices. Tetrabromobisphenol A (TBBPA), polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecanes (HBCDs) are main products of BFR on the market. In recent years, the types and quantities of BFRs into the environment have rapidly increased, the resulting environmental effects have been of great concern by international researches and toxicological studies on BFRs have become a hot issue in related fields. In this paper, the recent toxicological research of these three BFRs in endocrine-disrupting effect, hepatic toxicity, reproductive toxicity and neurotoxicity were summarized, the future research direction about their toxicity was discussed.