邻苯二甲酸二乙基己酯(DEHP)毒理与健康效应研究进展

王佳; 董四君

中国科学院城市环境研究所, 中国科学院城市环境与健康重点实验室, 厦门, 361021

作者简介: 王佳(1983-),女,博士,研究方向:环境毒理学、预防医学;E-mail:jwang@iue.ac.cn

基金项目:

中国科学院百人计划项目(KZCX2－YW－BR－18)

厦门市科技计划项目(3502Z20112019)

中图分类号: X171.5

Research Advances in Toxicology of DEHP and Its Health Effects

Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China

Fund Project:

摘要: 邻苯二甲酸二乙基己酯(DEHP)作为重要的聚氯乙烯塑料增塑剂在工业上应用广泛。目前,DEHP在海洋、大气、饮用水及动植物体内均被不同程度检出,对生态环境造成日益严重的污染。结合国内外毒理学研究成果,概述DEHP的人体暴露及代谢途径;并从肝脏、心脏、生殖发育系统和呼吸系统等方面详细探讨DEHP对动物健康的危害及其可能的毒性机制,以及对人体健康潜在的影响;在此基础上,对目前存在的问题及进一步研究的方向进行了探讨和展望。

Abstract: As an important plasticizer for polyvinyl chloride plastics, DEHP was widely used in industry, which was currently detected in the ocean, air, drinking water, animals and plants to different extent. DEHP has caused ever-increasing ecological environment pollution. In this paper, the domestic and foreign toxicological researches were reviewed, which were related to the human exposure and metabolic pathways of DEHP. The toxicity and potential danger of DEHP to animals and human health were discussed in detail from the aspect of liver, heart, reproductive/developmental system and respiratory system. On these bases, the existing problems and further research directions were pointed out.

Key words:

邻苯二甲酸二乙基己酯(DEHP)毒理与健康效应研究进展

作者简介: 王佳(1983-),女,博士,研究方向:环境毒理学、预防医学;E-mail:jwang@iue.ac.cn
中国科学院城市环境研究所, 中国科学院城市环境与健康重点实验室, 厦门, 361021

收稿日期: 2011-06-07

基金项目:

中国科学院百人计划项目(KZCX2－YW－BR－18)

厦门市科技计划项目(3502Z20112019)

关键词:

Research Advances in Toxicology of DEHP and Its Health Effects

Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China

Received Date: 2011-06-07

Fund Project:

Keywords:

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