不能将值 NULL 插入列 'id',表 'aje_website.dbo.t_web_site_access';列不允许有空值。INSERT 失败。 语句已终止。 欢迎访问《生态毒理学报》编辑部网站!

首页 | 期刊简介 | 编委会 | 投稿要求 | 化学品管理信息动态 | 学术会议 | 专辑 | 毒理学测试技术设备 | 订购本刊 | 联系我们 | English version

都慧丽1,2,尹乃毅1,2,张震南1,2,蔡晓琳1,2,李泽姣1,2,王鹏飞1,2,孙国新2,崔岩山1,2,*. 肠道微生物对土壤中铜、锌、锰生物可给性的影响[J]. 生态毒理学报, 2017, 12(3): 301-308
肠道微生物对土壤中铜、锌、锰生物可给性的影响
Effect of Human Gut Microbiota on Bioaccessibility of Soil Cu, Zn and Mn
投稿时间:2016-09-21  修订日期:2016-10-31
DOI:10.7524/AJE.1673-5897.20160921001
中文关键词:  金属  土壤  肠道微生物  SHIME模型  生物可给性  人体
英文关键词:metal  soil  human gut microbiota  SHIME model  bioaccessibility  human body
基金项目:国家自然科学基金项目(41271493)
作者单位
都慧丽1,2,尹乃毅1,2,张震南1,2,蔡晓琳1,2,李泽姣1,2,王鹏飞1,2,孙国新2,崔岩山1,2,* 1. 中国科学院大学 资源与环境学院北京 101408 2. 中国科学院生态环境研究中心北京 100085 
摘要点击次数: 397
全文下载次数: 183
中文摘要:
      为了更全面、准确地评价土壤中金属元素对人体的健康风险,研究土壤中金属元素在结肠阶段的生物可给性具有重要意义。通过采集我国一些地区的6种土壤,利用in vitro方法(PBET和SHIME联用) 研究土壤中Cu、Zn、Mn在胃、小肠、结肠阶段的生物可给性。研究显示,土壤中Cu、Zn、Mn在胃阶段的生物可给性分别为23.8%~63.0%、21.2%~64.4%、11.7%~35.6%;从胃阶段到小肠阶段,土壤中Cu的生物可给性提高了0.4%~14.4%,而土壤中Zn在小肠阶段的生物可给性降低了6.7%~38.7%。结肠阶段,土壤中Cu、Zn、Mn的生物可给性分别为2.4%~12.9%、5.7%~18.7%、6.2%~18.9%,与小肠阶段相比,分别降低了21.7%~56.9%、0.4%~36.8%、4.5%~19.1%。结果表明,在肠道微生物存在的情况下,土壤中Cu、Zn、Mn在结肠阶段有较低的人体健康风险。
  
AuthorAffiliation
Du Huili1,2,Yin Naiyi1,2,Zhang Zhennan1,2,Cai Xiaolin1,2,Li Zejiao1,2,Wang Pengfei1,2,Sun Guoxin2,Cui Yanshan1,2,*1. College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, China 2. Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
英文摘要:
      It is significantly important to investigate the bioaccessibility of the metal elements in the colon phase in order to assess the human health risks of metal elements in the soil comprehensively and accurately. Six soil samples were collected from some sites of China, and the bioaccessibility of soil Cu, Zn and Mn in the gastric, small intestinal and colon phases were determined using the physiologically based extraction test (PBET) combined with simulator of human intestinal microbial ecosystem (SHIME) model. In the gastric phase, the bioaccessibility of Cu, Zn and Mn was 23.8%-63.0%, 21.2%-64.4%, 11.7%-35.6%, respectively. In comparison with the values of gastric phase, Cu bioaccessibility increased 0.4%-14.4%, but Zn bioaccessibility decreased 6.7%-38.7% in the small intestinal phase. The bioaccessibility of Cu, Zn and Mn was 2.4%-12.9%, 5.7%-18.7%, 6.2%-18.9% in the colon phase, individually, which diminished 21.7%-56.9%, 0.4%-36.8%, 4.5%-19.1% compared with these of the small intestinal phase, separately. It could be concluded that these three metal elements (Cu, Zn and Mn) had a lower human health risk in the colon phase with human gut micobiota.
查看全文  查看/发表评论  下载PDF阅读器
关闭

您是第3317558位访问者   京ICP备 09058833 号

主办单位:中国科学院生态环境研究中心     单位地址:北京市海淀区双清路18号

 服务热线:010-62941072       传真:010-62923563       邮编:100085    Email: stdlxb@rcees.ac.cn

    本系统由北京勤云科技发展有限公司设计

0463美女美女3764美女美女ktv