不能将值 NULL 插入列 'id',表 'aje_website.dbo.t_web_site_access';列不允许有空值。INSERT 失败。 语句已终止。 欢迎访问《生态毒理学报》编辑部网站!

首页 | 期刊简介 | 编委会 | 投稿要求 | 化学品管理信息动态 | 学术会议 | 专辑 | 毒理学测试技术设备 | 订购本刊 | 联系我们 | English version

侯昌成1,赵玲1,*,尹平河2,#,陆钢1. 垃圾渗滤液中典型内分泌干扰物质(EDCs)细胞毒性分析[J]. 生态毒理学报, 2017, 12(3): 327-335
垃圾渗滤液中典型内分泌干扰物质(EDCs)细胞毒性分析
Cytotoxicity Analysis of Typical Endocrine Disrupting Chemicals (EDCs) in Landfill Leachate
投稿时间:2017-01-15  修订日期:2017-04-20
DOI:10.7524/AJE.1673-5897.20170115005
中文关键词:  垃圾渗滤液  内分泌干扰物质  人体乳腺癌细胞  细胞毒性  高级氧化过程  UV-Fenton  中间产物
英文关键词:landfill leachate  endocrine disrupting chemicals  MCE-7  cytotoxicity  advanced oxidation process  UV-Fenton  intermediate product
基金项目:国家自然基金项目(51508228,U113303,41676110);广东省产学研项目(2013B090600009);广东省科技计划项目(2014A020217007)
作者单位
侯昌成1,赵玲1,*,尹平河2,#,陆钢1 1. 暨南大学环境学院广州环境暴露与健康重点实验室广东环境污染与健康重点实验室广州 510632 2. 暨南大学生命科学技术学院暨南大学分析测试中心广州 510632 
摘要点击次数: 148
全文下载次数: 82
中文摘要:
      垃圾渗滤液的人类健康风险评估日益受到人们重视,也成为研究热点。本文采用一种新型高级氧化技术UV-Fenton处理渗滤液,并用人体乳腺癌细胞(MCF-7)评估处理过程中渗滤液原液以及渗滤液中典型内分泌干扰物质(EDCs)的细胞毒性,对垃圾渗滤液中EDCs的细胞毒性和变化规律进行了研究。结果表明渗滤液中的邻苯二甲酸二丁酯(DBP)、双酚A(BPA)、壬基酚(NP)是产生细胞毒性的主要物质,其毒性大小为DBP>BPA>NP。在同样的氧化降解过程中显示出不同毒性变化规律,通过GC-MS分析,结果显示UV-Fenton过程中产生了大量的中间产物,这也是引起毒性变化的主要原因。实验结果也说明垃圾渗滤液细胞毒性可以通过UV-Fenton过程有效去除。
  
AuthorAffiliation
Hou Changcheng1, Zhao Ling1,*, Yin Pinghe 2,#, Lu Gang11. School of Environment, Guangzhou Key Laboratory of Environmental Exposure and Health, Guangdong Key Laboratory of Environmental Pollution and Health, Jinan University, Guangzhou 510632, China 2. College of Life Science and Technology, Research Center of Analysis and Test, Jinan University, Guangzhou 510632, China
英文摘要:
      Recently, the health risk assessment on the landfill leachate has attracted increasing attentions and has become a research focus. In the present study, a novel advanced oxidation technology (UV-Fenton technology) was adopted to treat the leachate, and the cell toxicity of raw leachate and typical EDCs in the leachate in the treatment process has been evaluated by using human breast cancer cells (MCF-7). The results indicated that di-butyl phthalate (DBP), bisphenol A (BPA) and nonylphenol (NP) in the leachate were main substances which have significant cytotoxicity on MCF-7 cells. The toxicity variations of these three chemicals were different in the same oxidative degradation process, and the toxicity order was DBP > BPA > NP. According to the GC-MS analysis results, a great amount of intermediate products have been produced in UV-Fenton process, which may be a major reason that induced toxicity variations. The results implied that UV-Fenton technology is an effective method to reduce toxicity of landfill leachate.
查看全文  查看/发表评论  下载PDF阅读器
关闭

您是第3512245位访问者   京ICP备 09058833 号

主办单位:中国科学院生态环境研究中心     单位地址:北京市海淀区双清路18号

 服务热线:010-62941072       传真:010-62923563       邮编:100085    Email: stdlxb@rcees.ac.cn

    本系统由北京勤云科技发展有限公司设计

0463美女美女3764美女美女ktv