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马德华,张洪波,魏建建,黄宇辰,王连军*. 污水处理厂出水中抗雄激素样化合物控制的优先性研究[J]. 生态毒理学报, 2018, 13(6): 144-156
污水处理厂出水中抗雄激素样化合物控制的优先性研究
Control Priority Order of the Environmental Antiandrogens in Effluents of Wastewater Treatment Plants
投稿时间:2017-11-07  修订日期:2018-05-24
DOI:
中文关键词:  抗雄激素样化合物  内分泌干扰活性  生态风险  污水处理厂
英文关键词:environmental antiandrogens  endocrine disrupting activity  ecological risk  wastewater treatment plants
基金项目:国家自然科学基金(51708292);中央高校基本科研业务费专项资金(30918011307);国家重点实验室开放基金课题(17K07ESPCT)
作者单位
马德华,张洪波,魏建建,黄宇辰,王连军* 南京理工大学环境与生物工程学院江苏省化工污染控制与资源化重点实验室南京 210094 
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中文摘要:
      污水处理厂出水是环境中内分泌干扰物的重要来源之一。针对关注较少的抗雄激素样内分泌干扰物,在已有研究基础上,依据抗雄激素样化合物的抗雄激素样活性风险,建立了污水处理厂出水中抗雄激素样化合物控制的优先性排序方法。在污水处理厂出水中,共有147种疑似抗雄激素样化合物需要关注,主要为农药类,约占总数的60%。抗雄激素样活性风险排名前10%的化合物如下:邻苯二甲酸二丁酯、邻苯二甲酸二己酯、双酚A、溴螨酯、对叔辛基酚、腐霉利、烯菌酮、氯苯嘧啶醇、烯酰吗啉、杀螟松、十二烷基酚、敌草隆、咯菌酯、2-羟基-4'-甲氧基二苯甲酮、以及邻苯基苯酚。
  
AuthorAffiliation
Ma Dehua, Zhang Hongbo, Wei Jianjian, Huang Yuchen, Wang Lianjun*Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China
英文摘要:
      A major source of endocrine disrupting chemicals (EDCs) into the aquatic environment is the effluents of wastewater treatment plants (WWTPs). In the aquatic ecosystems, much of the EDCs research has concentrated on estrogenic compounds and in this study antiandrogenic compounds were paid attention to. On the basis of antiandrogenic activity risks, the approach to prioritizing antiandrogens in the effluents of WWTPs was constructed. In total, 147 antiandrogens had been reported and nearly 60% of which were pesticides. The developed procedure was applied and the first ten percent antiandrogens were as followed, dibutyl phthalate, di-n-hexyl phthalate, bisphenol A, bromopropylate, 4-t-octylphenol, procymidone, vinclozolin, fenarimol, dimethomorph, fenitrothion, 4-n-dodecylphenol, diuron, fludioxonil, 2-hydroxy-4'-methoxybenzophenone, and o-phenylphenol.
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