| Verner-Jeffreys D W,Shields R J,Bricknell I R,et al.Effects of different water treatment methods and antibioticaddition on larval survival and gut microflora development in Atlantic halibut (Hippoglossus hippoglossus L.) yolk-sac larvae[J].Aquaculture,2004,232(1/4):129-143 |
| 夏昆华,周鲁,郝丽芬.喹诺酮类抗生素的研究进展[J].国外医药(抗生素分册),2004,25(3):138-141Xia K H,Zhou L,Hao L F.Research progress of quinolone antibiotics[J].World Notes on Antibiotics,2004,25(3):138-141(in Chinese) |
| 中华人民共和国农业部.中华人民共和国农业部公告第2292号[EB/OL].(2015-09-01 )[2023-09-15].http://www.moa.gov.cn/nybgb/2015/jiuqi/201712/t20171219_6103873.htm |
| 刘桂英,葛坤,王召会,等.近岸海域抗生素污染状况的研究进展[J].渤海大学学报(自然科学版),2017,38(4):331-336Liu G Y,Ge K,Wang Z H,et al.Research progress on antibiotic pollution in coastal marine waters[J].Journal of Bohai University (Natural Science Edition),2017,38(4):331-336(in Chinese) |
| 杜鹃.黄渤海部分区域近岸海域中抗生素的分布、分配及释放动力学[D].大连:大连理工大学,2021:6-11Du J.Occurrence,distribution and desorption kinetics of antibiotics in regional coastal area of the Yellow Sea and the Bohai Sea[D].Dalian:Dalian University of Technology,2021:6 -11(in Chinese) |
| 赵富强,高会,张克玉,等.中国典型河流水域抗生素的赋存状况及风险评估研究[J].环境污染与防治,2021,43(1):94-102 Zhao F Q,Gao H,Zhang K Y,et al.Occurrence and risk assessment of antibiotics in typical river basins in China[J].Environmental Pollution&Control,2021,43(1):94-102(in Chinese) |
| Zou S C,Xu W H,Zhang R J,et al.Occurrence and distribution of antibiotics in coastal water of the Bohai Bay,China:Impacts of river discharge and aquaculture activities[J].Environmental Pollution,2011,159(10):2913-2920 |
| 闫如玉.上海市养殖场抗生素及其他药物的赋存特征与风险评估[D].上海:华东师范大学,2019:50-56Yan R Y.Occurrence characteristics and risk assessment of antibiotics and other drugs in Shanghai livestock farms[D].Shanghai:East China Normal University,2019:50 -56(in Chinese) |
| Chen K,Zhou J L.Occurrence and behavior of antibioticsin water and sediments from the Huangpu River,Shanghai,China[J].Chemosphere,2014,95:604-612 |
| 陈孝煊,吴志新,操玉涛.诺氟沙星对中华鳖消化道菌群的影响[J].华中农业大学学报,2002,21(3):269-272 Chen X X,Wu Z X,Cao Y T.Effect of norfloxacin on the microflora in the digestive tract of soft-shelled turtle (Trionyx sinensis)[J].Journal of Huazhong Agricultural,2002,21(3):269-272(in Chinese) |
| Chen H,Liu S,Xu X R,et al.Antibiotics in the coastal environment of the Hailing Bay Region,South China Sea:Spatial distribution,source analysis and ecological risks[J].Marine Pollution Bulletin,2015,95(1):365-373 |
| 贺诗静.诺氟沙星对斑马鱼胚胎的神经毒性及机制研究[D].武汉:武汉大学,2017:21-34He S J.Neurotoxicity of norfloxacin in zebrafish embryos (Danio rerio)[D].Wuhan:Wuhan University,2017:21 -34(in Chinese) |
| Liao X B,Zou R S,Li B X,et al.Biodegradation of chlortetracycline by acclimated microbiota[J].ProcessSafety and Environmental Protection,2017,109:11-17 |
| Zhao Y,Wang Q,Liu H,et al.High-throughput sequencing of 16S rRNA amplicons characterizes gut microbiota shift of juvenile sea cucumber Apostichopus japonicus feeding with three antibiotics[J].Journal of Oceanologyand Limnology,2019,37(5):1714-1725 |
| Flint H J,Scott K P,Louis P,et al.The role of the gut microbiota in nutrition and health[J].Nature Reviews Gastroenterology&Hepatology,2012,9(10):577-589 |
| Tzuc J T,Escalante D R,Rojas Herrera R,et al.Microbiota from Litopenaeus vannamei:Digestive tract microbial community of Pacific white shrimp (Litopenaeus vannamei)[J].SpringerPlus,2014,3:280 |
| Wang X H,Hu M H,Gu H X,et al.Short-term exposure to norfloxacin induces oxidative stress,neurotoxicity and microbiota alteration in juvenile large yellow croakerPseudosciaena crocea[J].Environmental Pollution,2020,267:115397 |
| Zhao X L,Li P,Zhang S Q,et al.Effects of environmental norfloxacin concentrations on the intestinal health and function of juvenile common carp and potential risk tohumans[J].Environmental Pollution,2021,287:117612 |
| Franco I,Regina A,Gil L,et al.Molecular characterization and susceptibility to antimicrobial drugs of isolated bacterials from shrimps (Litopenaeus vannamei)[J].Cab International,2010,49(7):2496-2501 |
| Xu R,Li L A,Zheng J H,et al.Combined toxic effects of nanoplastics and norfloxacin on mussel:Leveraging biochemical parameters and gut microbiota[J].The Science of the Total Environment,2023,880:163304 |
| 常亚青,隋锡林,李俊.刺参增养殖业现状、存在问题与展望[J].水产科学,2006,25(4):198-201 Chang Y Q,Sui X L,Li J.The current situation,problemand prospect on the Apostichopus japonicus aquaculture[J].Fisheries Science,2006,25(4):198-201(in Chinese) |
| 刘美如.辽宁省不同地区春季刺参肠道菌群分析与比较[D].大连:大连海洋大学,2018:7-8Liu M R.Analysis and comparison on intestinal microbiota of sea cucumber Apostichopus japonicus from different habitats in spring in Liaoning Province[D].Dalian:Dalian Ocean University,2018:7 -8(in Chinese) |
| 王紫薇.进食阶段仿刺参肠道菌群多样性和可培养细菌活性的研究[D].哈尔滨:哈尔滨工业大学,2021:7-15Wang Z W.The diversity of intestinal microflora and the bioactivities of culturable bacteria associated with sea cumumber Apostichopus japonicus at the feeding stage[D].Harbin:Harbin Institute of Technology,2021:7 -15(inChinese) |
| Díaz-Díaz L M,Rosario-Meléndez N,RodríguezVillafañe A,et al.Antibiotics modulate intestinal regeneration[J].Biology,2021,10(3):236 |
| 林志萍.磺胺甲恶唑胁迫下刺参肠道菌群及宿主代谢特征研究[D].大连:大连海洋大学,2023:21-30Lin Z P.Study on intestinal flora and host metabolic characteristics of sea cucumber (Apostichopus japonicus) under sulfamethoxazole stress[D].Dalian:Dalian Ocean University,2023:21 -30(in Chinese) |
| 李石磊,杨慧花,张乾,等.药浴对仿刺参幼参肠道菌群的影响[J].水产科学,2023,42(5):871-877 Li S L,Yang H H,Zhang Q,et al.Effects of medicated bath on gut microbiota of juvenile sea cucumber Apostichopus japonicus[J].Fisheries Science,2023,42(5):871-877(in Chinese) |
| Bradford M M.A rapid and sensitive method for the quantitation of microgram quantities of protein utilizingthe principle of protein-dye binding[J].Analytical Biochemistry,1976,72:248-254 |
| Xu R,Li L A,Zheng J H,et al.Combined toxic effects of nanoplastics and norfloxacin on mussel:Leveraging biochemical parameters and gut microbiota[J].The Science of the Total Environment,2023,880:163304 |
| Tang L,Feng L,Sun C Y,et al.Effect of tryptophan ongrowth,intestinal enzyme activities and TOR gene expression in juvenile Jian carp (Cyprinus carpio var.Jian):Studies in vivo and in vitro[J].Aquaculture,2013,412-413:23-33 |
| Bao N,Ren T J,Han Y Z,et al.Alteration of growth,intestinal Lactobacillus,selected immune and digestive enzyme activities in juvenile sea cucumber Apostichopus japonicus,fed dietary multiple probiotics[J].AquacultureInternational,2017,25(5):1721-1731 |
| Gao F,Yang H S,Xu Q,et al.Effect of water temperatureon digestive enzyme activity and gut mass in sea cucumber Apostichopus japonicus (Selenka),with special reference to aestivation[J].Chinese Journal of Oceanologyand Limnology,2009,27(4):714-722 |
| Limbu S M,Zhou L,Sun S X,et al.Chronic exposure to low environmental concentrations and legal aquaculturedoses of antibiotics cause systemic adverse effects in Niletilapia and provoke differential human health risk[J].Environment International,2018,115:205-219 |
| Yan F J,Tian X L,Dong S L,et al.Growth performance,immune response,and disease resistance against Vibriosplendidus infection in juvenile sea cucumber Apostichopus japonicus fed a supplementary diet of the potentialprobiotic Paracoccus marcusii DB11[J].Aquaculture,2014,420-421:105-111 |
| Qiao R X,Sheng C,Lu Y F,et al.Microplastics induceintestinal inflammation,oxidative stress,and disorders of metabolome and microbiome in zebrafish[J].The Science of the Total Environment,2019,662:246-253 |
| Solomando A,CapóX,Alomar C,et al.Long-term exposure to microplastics induces oxidative stress and a proinflammatory response in the gut of Sparus aurata Linnaeus,1758[J].Environmental Pollution,2020,266(Pt1):115295 |
| Bachali S,Jager M,Hassanin A,et al.Phylogenetic analysis of invertebrate lysozymes and the evolution of lysozyme function[J].Journal of Molecular Evolution,2002,54(5):652-664 |
| Liang X M,Wang F,Li K B,et al.Effects of norfloxacin nicotinate on the early life stage of zebrafish (Danio rerio):Developmental toxicity,oxidative stress and immunotoxicity[J].Fish&Shellfish Immunology,2020,96:262-269 |
| Thaiss C A,Zmora N,Levy M,et al.The microbiomeand innate immunity[J].Nature,2016,535(7610):65-74 |
| Zhang M L,Shan C J,Tan F,et al.Gnotobiotic models:Powerful tools for deeply understanding intestinal microbiota-host interactions in aquaculture[J].Aquaculture,2020,517:734800 |
| Daniel L,Erik R,Myklebust R,et al.Dietary Effect of Soybean (Glycine max) Products on Gut Histology andMicrobiota of Fish[M]//El-Shemy H.Soybean and Nutrition.InTech,2011:231-250 |
| Uyaguari M,Key P,Moore J,et al.Acute effects of theantibiotic oxytetracycline on the bacterial community of the grass shrimp,Palaemonetes pugio[J].EnvironmentalToxicology and Chemistry,2009,28(12):2715-2724 |
| 洪嘉炜.恩诺沙星对三种经济贝类肠道微生物群落的影响[D].海口:海南大学,2019:26-35Hong J W.Effects of enrofloxacin on intestinal microbial community in three economic shellfish[D].Haikou:Hainan University,2019:26 -35(in Chinese) |
| 苗淑彦,韩蓓,胡俊涛,等.饲料中添加不同浓度四环素对乌鳢生长性能、肠道菌群组成和组织形态的影响[J].动物营养学报,2019,31(12):5813-5822 Miao S Y,Han B,Hu J T,et al.Effects of dietary differentconcentrations of tetracycline on growth performance,intestinal microbiota composition and morphology of Channa argus[J].Chinese Journal of Animal Nutrition,2019,31(12):5813-5822(in Chinese) |
| Wang L,Zhao X W,Xu H C,et al.Characterization of the bacterial community in different parts of the gut of sea cucumber (Apostichopus japonicus) and its variationduring gut regeneration[J].Aquaculture Research,2018,49(5):1987-1996 |
| Zhang Z,Xing R L,Lv Z M,et al.Analysis of gut microbiota revealed Lactococcus garviaeae could be an indicative of skin ulceration syndrome in farmed sea cucumberApostichopus japonicus[J].Fish&Shellfish Immunology,2018,80:148-154 |
| 王轶南,朱世伟,常亚青.刺参肠道及养殖池塘菌群组成的PCR-DGGE指纹图谱分析[J].渔业科学进展,2010,31(3):119-122 Wang Y N,Zhu S W,Chang Y Q.PCR-DGGE analysis of bacterial community composition in the intestine and aquaculture pond of Apostichopus japonicus[J].Progressin Fishery Sciences,2010,31(3):119-122(in Chinese) |
| Cardona E,Gueguen Y,MagréK,et al.Bacterial community characterization of water and intestine of the shrimpLitopenaeus stylirostris in a biofloc system[J].BMC Microbiology,2016,16(1):157 |
| Morrison M,Pope P B,Denman S E,et al.Plant biomass degradation by gut microbiomes:More of the same or something new?[J].Current Opinion in Biotechnology,2009,20(3):358-363 |
| Yan W,Hall A B,Jiang X F.Bacteroidales species in thehuman gut are a reservoir of antibiotic resistance genesregulated by invertible promoters[J].NPJ Biofilms andMicrobiomes,2022,8(1):1-9 |
| Pumbwe L,Ueda O,Yoshimura F,et al.Bacteroides fragilis BmeABC efflux systems additively confer intrinsic antimicrobial resistance[J].The Journal of AntimicrobialChemotherapy,2006,58(1):37-46 |
| Bartha N A,Sóki J,Urbán E,et al.Investigation of the prevalence of tetQ,tetX and tetX1 genes in Bacteroides strains with elevated tigecycline minimum inhibitory concentrations[J].International Journal of Antimicrobial Agents,2011,38(6):522-525 |
| Li P,Chen C Z,Zhao X L,et al.Metagenomics analysis reveals the effects of norfloxacin on the gut microbiota of juvenile common carp (Cyprinus carpio)[J].Chemosphere,2023,325:138389 |
| Jooste P J,Hugo C J.The taxonomy,ecology and cultivation of bacterial genera belonging to the family Flavobacteriaceae[J].International Journal of Food Microbiology,1999,53(2-3):81-94 |
| Shindo K,Kikuta K,Suzuki A,et al.Rare carotenoids,(3R)-saproxanthin and (3R,2'S)-myxol,isolated from novel marine bacteria (Flavobacteriaceae) and their antioxidative activities[J].Applied Microbiology and Biotechnology,2007,74(6):1350-1357 |
| Sakai T,Kimura H,Kato I.A marine strain of Flavobacteriaceae utilizes brown seaweed fucoidan[J].Marine Biotechnology,2002,4(4):399-405 |
| Thomson K S.Antibiotic resistance of Flavobacteriumand related genera[D].Hobart:University of Tasmania,1988:16-24 |
| Bernardet J F,Bowman J P.The Genus Flavobacterium[J].The Prokaryotes,2006,7:481-531 |
| Wu Z B,Zhang Q Q,Lin Y Y,et al.Taxonomic and functional characteristics of the gill and gastrointestinal microbiota and its correlation with intestinal metabolitesin NEW GIFT strain of farmed adult Nile tilapia (Oreochromis niloticus)[J].Microorganisms,2021,9(3):617 |
| Bartoskova M,Dobsikova R,Stancova V,et al.Norfloxacin:Toxicity for zebrafish (Danio rerio) focused on oxidative stress parameters[J].BioMed Research International,2014,2014:560235 |
| Zivna D,Plhalova L,Praskova E,et al.Oxidative stressparameters in fish after subchronic exposure to acetylsalicylic acid[J].Neuro Endocrinology Letters,2013,34(Suppl 2):116-122 |
| Behera B K,Paria P,Das A,et al.Molecular characterization and pathogenicity of a virulent Acinetobacter baumannii associated with mortality of farmed Indian majorcarp Labeo rohita (Hamilton 1822)[J].Aquaculture,2017,471:157-162 |
| Ryan M P,Adley C C.Ralstonia spp.:Emerging global opportunistic pathogens[J].European Journal of ClinicalMicrobiology&Infectious Diseases,2014,33(3):291-304 |
| Rungrassamee W,Klanchui A,Maibunkaew S,et al.Bacterial dynamics in intestines of the black tiger shrimp andthe Pacific white shrimp during Vibrio harveyi exposure[J].Journal of Invertebrate Pathology,2016,133:12-19 |
| Xiong J B,Dai W F,Li C H.Advances,challenges,and directions in shrimp disease control:The guidelines froman ecological perspective[J].Applied Microbiology andBiotechnology,2016,100(16):6947-6954 |
| Cottrell M T,Kirchman D L.Natural assemblages of marine proteobacteria and members of the Cytophaga-Flavobacter cluster consuming low-and high-molecularweight dissolved organic matter[J].Applied and Environmental Microbiology,2000,66(4):1692-1697 |
| Schwalm N D 3rd,Groisman E A.Navigating the gutbuffet:Control of polysaccharide utilization in Bacteroides spp.[J].Trends in Microbiology,2017,25(12):1005-1015 |
| Lombard V,Golaconda Ramulu H,Drula E,et al.Thecarbohydrate-active enzymes database (CAZy) in 2013[J].Nucleic Acids Research,2014,42(Database issue):D490-D495 |
| Sonnenburg J L,Xu J,Leip D D,et al.Glycan foragingin vivo by an intestine-adapted bacterial symbiont[J].Science,2005,307(5717):1955-1959 |
| 陈琼,李贵阳,罗坤,等.凡纳滨对虾(Litopenaeus vannamei)亲虾繁殖期水体微生物多样性[J].海洋与湖沼,2017,48(1):130-138 Chen Q,Li G Y,Luo K,et al.Microbial diversity in broodstock waters of the two genders of Litopenaeus vannamei[J].Oceanologia et Limnologia Sinica,2017,48(1):130-138(in Chinese) |
| Xia B,Gao Q F,Wang J Y,et al.Effects of dietary carbohydrate level on growth,biochemical composition andglucose metabolism of juvenile sea cucumber Apostichopus japonicus (Selenka)[J].Aquaculture,2015,448:63-70 |
| Li M M,Shang Q S,Li G S,et al.Degradation of marinealgae-derived carbohydrates by bacteroidetes isolated from human gut microbiota[J].Marine Drugs,2017,15(4):92 |