| Managaki S, Murata A, Takada H, et al. Distribution of macrolides, sulfonamides, and trimethoprim in tropical waters:Ubiquitous occurrence of veterinary antibiotics in the Mekong Delta[J]. Environmental Science & Technology, 2007, 41(23):8004-8010 |
| Jiang L, Hu X, Yin D, et al. Occurrence, distribution and seasonal variation of antibiotics in the Huangpu River, Shanghai, China[J]. Chemosphere, 2011, 82(6):822-828 |
| Qin Y, Wen Q, Ma Y, et al. Antibiotics pollution in Gonghu Bay in the period of water diversion from Yangtze River to Taihu Lake[J]. Environmental Earth Sciences, 2018, 77(11):419 |
| Li Y, Wu X, Mo C, et al. Investigation of sulfonamide, tetracycline, and quinolone antibiotics in vegetable farmland soil in the Pearl River Delta Area, Southern China[J]. Journal of Agricultural and Food Chemistry, 2011, 59(13):7268-7276 |
| Hartmann E M, Hickey R, Hsu T, et al. Antimicrobial chemicals are associated with elevated antibiotic resistance genes in the indoor dust microbiome[J]. Environmental Science & Technology, 2016, 50(18):9807-9815 |
| Zhang Q, Ying G, Pan C, et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of China:Source analysis, multimedia modeling, and linkage to bacterial resistance[J]. Environmental Science & Technology, 2015, 49(11):6772-6782 |
| Wright G D. Antibiotic resistance in the environment:A link to the clinic?[J]. Current Opinion In Microbiology, 2010, 13(5):589-594 |
| Tripathi V, Tripathi P. Antibiotic Resistance Genes:An Emerging Environmental Pollutant[M]. Kesari K K. Environmental Science and Engineering. Springer, 2017:183-201 |
| Li S, Shi W, Liu W, et al. A duodecennial national synthesis of antibiotics in China's major rivers and seas (2005-2016)[J]. Science of the Total Environment, 2018, 615:906-917 |
| Ghosh S, Lapara T M. The effects of subtherapeutic antibiotic use in farm animals on the proliferation and persistence of antibiotic resistance among soil bacteria[J]. The ISME Journal, 2007, 1(3):191-203 |
| Zhao R, Feng J, Liu J, et al. Deciphering of microbial community and antibiotic resistance genes in activated sludge reactors under high selective pressure of different antibiotics[J]. Water Research, 2019, 151:388-402 |
| Zhang Q, Jia A, Wan Y, et al. Occurrences of three classes of antibiotics in a natural river basin:Association with antibiotic-resistant Escherichia coli[J]. Environmental Science & Technology, 2014, 48(24):14317-14325 |
| Rodriguez-Mozaz S, Chamorro S, Marti E, et al. Occurrence of antibiotics and antibiotic resistance genes in hospital and urban wastewaters and their impact on the receiving river[J]. Water Research, 2015, 69:234-242 |
| Hurst J J, Oliver J P, Schueler J, et al. Trends in antimicrobial resistance genes in manure blend pits and long-term storage across dairy farms with comparisons to antimicrobial usage and residual concentrations[J]. Environmental Science & Technology, 2019, 53(5):2405-2415 |
| Jia J, Guan Y, Cheng M, et al. Occurrence and distribution of antibiotics and antibiotic resistance genes in Ba River, China[J]. Science of the Total Environment, 2018, 642:1136-1144 |
| Martinez J L, Baquero F. Mutation frequencies and antibiotic resistance[J]. Antimicrobial Agents and Chemotherapy, 2000, 44(7):1771-1777 |
| Davison J. Genetic exchange between bacteria in the environment[J]. Plasmid, 1999, 42(2):73-91 |
| 谢志雄, 沈萍. 细菌遗传转化与水平基因转移[J]. 中南民族大学学报:自然科学版, 2003(4):1-5 Xie Z X, Shen P. Bacterial genetic transformation and horizontal gene transfer[J]. Journal of Central South University for Nationalities:Natural Science, 2003 (4):1-5(in Chinese) |
| Solomon J M, Grossman A D. Who's competent and when:Regulation of natural genetic competence in bacteria[J]. Trends in Genetics, 1996, 12(4):150-155 |
| 黄锦岭. 水平基因转移及其发生机制[J]. 科学通报, 2017, 62(12):1221-1225 Huang J L. Horizontal gene transfer and its mechanism[J]. Chinese Science Bulletin, 2017, 62(12):1221-1225(in Chinese) |
| Lerminiaux N A, Cameron A D S. Horizontal transfer of antibiotic resistance genes in clinical environments[J]. Canadian Journal of Microbiology, 2019, 65(1):34-44 |
| Zhou L, Ying G, Liu S, et al. Excretion masses and environmental occurrence of antibiotics in typical swine and dairy cattle farms in China[J]. Science of the Total Environment, 2013, 444:183-195 |
| Hall B M, Ma C, Liang P, et al. Fluctuation analysis calculator:A web tool for the determination of mutation rate using Luria-Delbruck fluctuation analysis[J]. Bioinformatics, 2009, 25(12):1564-1565 |
| Seydel J K. Sulfonamides, structure-activity relationship, and mode of action. Structural problems of the antibacterial action of 4-aminobenzoic acid (PABA) antagonists[J]. Journal of Pharmaceutical Sciences, 1968, 57(9):1455-1478 |
| Brown G M. The biosynthesis of folic acid. Ⅱ. Inhibition by sulfonamides[J]. The Journal of Biological Chemistry, 1962, 237(6):536-540 |
| Skold O. Sulfonamide resistance:Mechanisms and trends[J]. Drug Resistance Updates, 2000, 3(3):155-160 |
| Wang T, Liu Y, Wang D, et al. The joint effects of sulfonamides and quorum sensing inhibitors on Vibrio fischeri:Differences between the acute and chronic mixed toxicity mechanisms[J]. Journal of Hazardous Materials, 2016, 310:56-67 |
| Vedantam G, Guay G G, Austria N E, et al. Characterization of mutations contributing to sulfathiazole resistance in Escherichia coli[J]. Antimicrobial Agents and Chemotherapy, 1998, 42(1):88-93 |
| Sultan I, Rahman S, Jan A T, et al. Antibiotics, resistome and resistance mechanisms:A bacterial perspective[J]. Frontiers in Microbiology, 2018, 9:2066 |
| Andersson D I, Hughes D. Microbiological effects of sublethal levels of antibiotics[J]. Nature Reviews Microbiology, 2014, 12(7):465-478 |
| Thomas C M, Nielsen K M. Mechanisms of, and barriers to, horizontal gene transfer between bacteria[J]. Nature Reviews Microbiology, 2005, 3(9):711-721 |
| Sorensen S J, Bailey M, Hansen L H, et al. Studying plasmid horizontal transfer in situ:A critical review[J]. Nature Reviews Microbiology, 2005, 3(9):700-710 |
| Wang Y, Lu J, Mao L, et al. Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera[J]. The ISME Journal, 2019, 13(2):509-522 |
| Zhang Y, Gu A Z, Cen T, et al. Sub-inhibitory concentrations of heavy metals facilitate the horizontal transfer of plasmid-mediated antibiotic resistance genes in water environment[J]. Environmental Pollution, 2018, 237:74-82 |
| Bae Y S, Oh H, Rhee S G, et al. Regulation of reactive oxygen species generation in cell signaling[J]. Molecules and Cells, 2011, 32(6):491-509 |
| Schieber M, Chandel N S. ROS function in redox signaling and oxidative stress[J]. Current Biology, 2014, 24(10):R453-R462 |
| Xie Y, Wei Y, Shen Y, et al. TADB 2.0:An updated database of bacterial type Ⅱ toxin-antitoxin loci[J]. Nucleic Acids Research, 2018, 46(D1):D749-D753 |
| Harms A, Maisonneuve E, Gerdes K. Mechanisms of bacterial persistence during stress and antibiotic exposure[J]. Science, 2016, 354(6318):f4268 |
| Maslowska K H, Makiela Dzbenska K, Fijalkowska I J. The SOS system:A complex and tightly regulated response to DNA damage[J]. Environmental and Molecular Mutagenesis, 2019, 60(4):368-384 |
| Kim S, Yun Z, Ha U, et al. Transfer of antibiotic resistance plasmids in pure and activated sludge cultures in the presence of environmentally representative micro-contaminant concentrations[J]. Science of the Total Environment, 2014, 468-469:813-820 |
| Hu J, Shi J, Chang H, et al. Phenotyping and genotyping of antihiotic-resistant Escherichia coli isolated from a natural river basin[J]. Environmental Science & Technology, 2008, 42(9):3415-3420 |