| Faria M, Lopez M A, Fernandez-Sanjuan M, et al. Comparative toxicity of single and combined mixtures of selected pollutants among larval stages of the native freshwater mussels (Unio elongatulus) and the invasive zebra mussel (Dreissena polymorpha)[J]. Science of the Total Environment, 2010, 408(12):2452-2458 |
| Boxall A B, Fogg L A, Blackwell P A, et al. Veterinary medicines in the environment[J]. Reviews of Environmental Contamination and Toxicology, 2004, 180:1-91 |
| 魏维芮. 浅谈我国抗生素的滥用问题及对策[J]. 化工管理, 2018(3):92, 94 |
| Ben W, Qiang Z, Adams C, et al. Simultaneous determination of sulfonamides, tetracyclines and tiamulin in swine wastewater by solid-phase extraction and liquid chromatography-mass spectrometry[J]. Journal of Chromatography A, 2008, 1202(2):173-180 |
| 徐永刚, 宇万太, 马强, 等. 环境中抗生素及其生态毒性效应研究进展[J]. 生态毒理学报, 2015, 10(3):11-27 Xu Y G, Yu W T, Ma Q, et al. The antibiotic in environment and its ecotoxicity:A review[J]. Asian Journal of Ecotoxicology, 2015, 10(3):11-27(in Chinese) |
| 雷慧宁. 规模化猪场废水处理工艺中抗生素和重金属残留及其生态风险[D]. 上海:华东师范大学, 2016:26 Lei H N. Antibiotic and heavy metal residues and ecological risks in large-scale pig farm wastewater treatment process[D]. Shanghai:East China Normal University, 2016:26(in Chinese) |
| Yu X, Wu Y, Deng M, et al. Tetracycline antibiotics as PI3K inhibitors in the Nrf2-mediated regulation of antioxidative stress in zebrafish larvae[J]. Chemosphere, 2019, 226:696-703 |
| Meyer M T, Bumgarner J E, Varns J L, et al. Use of radioimmunoassay as a screen for antibiotics in confined animal feeding operations and confirmation by liquid chromatography/mass spectrometry[J]. Science of the Total Environment, 2000, 248(2-3):181-187 |
| Keerthisinghe T P, Wang F, Wang M, et al. Long-term exposure to TET increases body weight of juvenile zebrafish as indicated in host metabolism and gut microbiome[J]. Environment Internationnal, 2020, 139:105705 |
| Qiu W, Sun J, Fang M, et al. Occurrence of antibiotics in the main rivers of Shenzhen, China:Association with antibiotic resistance genes and microbial community[J]. Science of the Total Environment, 2019, 653:334-341 |
| Yuan J, Ni M, Liu M, et al. Occurrence of antibiotics and antibiotic resistance genes in a typical estuary aquaculture region of Hangzhou Bay, China[J]. Marine Pollution Bulletin, 2019, 138:376-384 |
| Zhu Y G, Johnson T A, Su J Q, et al. Diverse and abundant antibiotic resistance genes in Chinese swine farms[J]. Proceedings of the National Academy of Sciences of the United States of America, 2013, 110(9):3435-3440 |
| Franco G C, Kajiya M, Nakanishi T, et al. Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo[J]. Experimental Cell Research, 2011, 317(10):1454-1464 |
| Kim Y, Kim J, Lee H, et al. Tetracycline analogs inhibit osteoclast differentiation by suppressing MMP-9-mediated histone H3 cleavage[J]. International Journal of Molecular Sciences, 2019, 20(16):4038 |
| Dorman G, Cseh S, Hajdu I, et al. Matrix metalloproteinase inhibitors:A critical appraisal of design principles and proposed therapeutic utility[J]. Drugs, 2010, 70(8):949-964 |
| Vandooren J, Knoops S, Aldinucci Buzzo J L, et al. Differential inhibition of activity, activation and gene expression of MMP-9 in THP-1 cells by azithromycin and minocycline versus bortezomib:A comparative study[J]. PLoS One, 2017, 12(4):e0174853 |
| Dong W, Hinton D E, Kullman S W. TCDD disrupts hypural skeletogenesis during medaka embryonic development[J]. Toxicological Sciences, 2012, 125(1):91-104 |
| Zhang G, Eames B F, Cohn M J. Chapter 2. Evolution of vertebrate cartilage development[J]. Current Topics in Developmental Biology, 2009, 86:15-42 |
| Karsenty G. Transcriptional control of skeletogenesis[J]. Annual Review of Genomics and Human Genetics, 2008, 9:183-196 |
| Flores M V, Lam E Y, Crosier P, et al. A hierarchy of Runx transcription factors modulate the onset of chondrogenesis in craniofacial endochondral bones in zebrafish[J]. Developmental Dynamics, 2006, 235(11):3166-3176 |
| Enomoto H, Furuichi T, Zanma A, et al. Runx2 deficiency in chondrocytes causes adipogenic changes in vitro[J]. Journal of Cell Science, 2004, 117:417-425 |
| Bell D M, Leung K K, Wheatley S C, et al. SOX9 directly regulates the type-Ⅱ collagen gene[J]. Nature Genetics, 1997, 16(2):174-178 |
| Lefebvre V, Huang W, Harley V R, et al. SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(Ⅱ) collagen gene[J]. Molecular and Cellular Biology, 1997, 17(4):2336-2346 |
| Sekiya I, Tsuji K, Koopman P, et al. SOX9 enhances aggrecan gene promoter/enhancer activity and is up-regulated by retinoic acid in a cartilage-derived cell line, TC6[J]. The Journal of Biological Chemistry, 2000, 275(15):10738-10744 |
| Bridgewater L C, Lefebvre V, de Crombrugghe B. Chondrocyte-specific enhancer elements in the Col11a2 gene resemble the Col2a1 tissue-specific enhancer[J]. The Journal of Biological Chemistry, 1998, 273(24):14998-15006 |
| Goldring M B, Peng H, Ijiri K, et al. ESE1 inhibits COL2A1 promoter activity via Sox9 and CBP[J]. Matrix Biology, 2006, 25(S1):S90 |
| 何加发. 诺氟沙星对稀有鮈鲫雌性亲本胚胎及子代骨骼发育的影响[D]. 杨凌:西北农林科技大学, 2019:1 He J F. The influence of embryo and bone development treated with norfloxacin in rare minnow Gobiocypris rarus offspring[D]. Yangling:Northwest A&F University, 2019:1(in Chinese) |
| Crump J G, Swartz M E, Eberhart J K, et al. Moz-dependent Hox expression controls segment-specific fate maps of skeletal precursors in the face[J]. Development, 2006, 133(14):2661-2669 |
| Dutton J R, Antonellis A, Carney T J, et al. An evolutionarily conserved intronic region controls the spatiotemporal expression of the transcription factor Sox10[J]. BMC Developmental Biology, 2008, 8:105 |
| Halpern M E, Hatta K, Amacher S L, et al. Genetic interactions in zebrafish midline development[J]. Developmental Biology, 1997, 187(2):154-170 |
| Renn J, Winkler C, Schartl M, et al. Zebrafish and medaka as models for bone research including implications regarding space-related issues[J]. Protoplasma, 2006, 229(2-4):209-214 |
| Brannen K C, Panzica-Kelly J M, Danberry T L, et al. Development of a zebrafish embryo teratogenicity assay and quantitative prediction model[J]. Birth Defects Research Part B, Developmental and Reproductive Toxicology, 2010, 89(1):66-77 |
| Dong W, Wang F, Fang M, et al. Use of biological detection methods to assess dioxin-like compounds in sediments of Bohai Bay, China[J]. Ecotoxicology and Environmental Safety, 2019, 173:339-346 |
| Osman A G, Wuertz S, Mekkawy I A, et al. Lead induced malformations in embryos of the African catfish Clarias gariepinus (Burchell, 1822)[J]. Environmental Toxicology, 2007, 22(4):375-389 |
| 梁伟放, 赵建国, 柳贤德. 四环素对斑马鱼胚胎发育及CAT和SOD活性的影响[J]. 热带农业工程, 2017, 41(1):17-20 Liang W F, Zhao J G, Liu X D, et al. Effect of tetracycline on zebrafish embryonic development and CAT and SOD activities[J]. Tropical Agricultural Engineering, 2017, 41(1):17-20(in Chinese) |
| Jonsson M E, Kubota A, Timme-Laragy A R, et al. Ahr2-dependence of PCB126 effects on the swim bladder in relation to expression of CYP1 and cox-2 genes in developing zebrafish[J]. Toxicology and Applied Pharmacology, 2012, 265(2):166-174 |
| Yabe K, Satoh H, Ishii Y, et al. Early pathophysiologic feature of arthropathy in juvenile dogs induced by ofloxacin, a quinolone antimicrobial agent[J]. Veterinary Pathology, 2004, 41(6):673-681 |
| Goto K, Yabe K, Suzuki T, et al. Chondrotoxicity and toxicokinetics of novel quinolone antibacterial agents DC-159a and DX-619 in juvenile rats[J]. Toxicology, 2010, 276(2):122-127 |
| Bi W, Deng J M, Zhang Z, et al. Sox9 is required for cartilage formation[J]. Nature Genetics, 1999, 22(1):85-89 |
| Akiyama H, Chaboissier M C, Martin J F, et al. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6[J]. Genes & Development, 2002, 16(21):2813-2828 |
| Cheah K S, Au P K, Lau E T, et al. The mouse Col2a-1 gene is highly conserved and is linked to Int-1 on chromosome 15[J]. Mammalian Genome, 1991, 1(3):171-183 |
| Wood A, Ashhurst D E, Corbett A, et al. The transient expression of type Ⅱ collagen at tissue interfaces during mammalian craniofacial development[J]. Development, 1991, 111(4):955-968 |
| Li S W, Khillan J, Prockop D J. The complete cDNA coding sequence for the mouse pro alpha 1(Ⅰ) chain of type Ⅰ procollagen[J]. Matrix Biology, 1995, 14(7):593-595 |
| Cheah K S, Lau E T, Au P K, et al. Expression of the mouse alpha 1(Ⅱ) collagen gene is not restricted to cartilage during development[J]. Development, 1991, 111(4):945-953 |