猪粪堆肥过程中四环素类抗生素的生物转化及降解研究进展
Advances in Biotransformation and Degradation of Tetracycline Antibiotics During Composting of Pig Manure
-
摘要: 四环素类抗生素（TCs）是畜禽养殖业中一类重要的兽药。随着畜禽养殖集约化，越来越多的抗生素经畜禽机体代谢进入环境，导致了对人类健康和生物安全等的危害。堆肥是无害化去除畜禽粪便中TCs的常见方法，能最大程度削减畜禽粪便中TCs的残留。笔者根据国内堆肥处理猪粪中抗生素残留的现状，结合国内外猪粪堆肥化技术的最新研究进展，从TCs生物转化、生物和非生物降解途径，阐述了猪粪堆肥过程中环境因子的调控、微生物群落结构与组成的变化和TCs的生物降解机制，旨在为未来畜禽粪便无害化、肥料资源化利用提供理论依据和技术参考。Abstract: Tetracycline antibiotics (TCs) are an important class of veterinary drugs in the livestock and poultry industry. With the intensification of livestock and poultry farming, more and more antibiotics are metabolized into the environment through the livestock and poultry organisms, increasing the harm to human health and biosecurity. Composting is a common method for harmlessly removing TCs from livestock manure, which can minimize the residue of TCs in livestock manure. Based on the domestic status of antibiotic residues in pig manure treated by composting, combined with the latest research progress of domestic and foreign pig manure composting technology, this paper expounds the regulation of environmental factors, the change of microbial community structure and composition, and the biodegradation mechanism of TCs in the process of pig manure composting from the aspects of TCs biotransformation, biological and non-biological degradation. This paper aims to provide theoretical basis and technical reference for the harmless livestock manure utilization in the future.
-
-
Zhang Q Q, Ying G G, Pan C G, et al. Comprehensive evaluation of antibiotics emission and fate in the river basins of China:Source analysis, multimedia modeling, and linkage to bacterial resistance[J]. Environmental Science & Technology, 2015, 49(11):6772-6782 于晓雯, 索全义. 畜禽粪便中四环素类抗生素的残留及危害[J]. 北方农业学报, 2018, 46(3):83-88 Yu X W, Suo Q Y. Residues and hazards of tetracycline antibiotics in livestock and poultry manure[J]. Journal of Northern Agriculture, 2018, 46(3):83-88(in Chinese)
刑廷铣. 畜牧业生产对生态环境的污染及其防治[J]. 环境科学导刊, 2001, 20(1):39-43 Xing T X. Animal husbandry production pollution[J]. Environmental Science Survey, 2001, 20(1):39-43(in Chinese)
黎运红. 畜禽粪便资源化利用潜力研究[D]. 武汉:华中农业大学, 2015:7 Li Y H. Study on the potential utilization of livestock manure resources[D]. Wuhan:Huazhong Agricultural University, 2015:7(in Chinese) 成登苗, 李兆君, 张雪莲, 等. 畜禽粪便中兽用抗生素削减方法的研究进展[J]. 中国农业科学, 2018, 51(17):3335-3352 Cheng D M, Li Z J, Zhang X L, et al. Advances in research on methods for reducing veterinary antibiotics in livestock manure[J]. Scientia Agricultura Sinica, 2018, 51(17):3335-3352(in Chinese)
余慎, 王敏, 洪有为, 等. 环境介质中的抗生素及其微生物生态效应[J]. 生态学报, 2011, 31(15):4437-4446 Yu S, Wang M, Hong Y W, et al. Antibiotics in environmental matrices and their effects on microbial ecosystems[J]. Acta Ecologica Sinica, 2011, 31(15):4437-4446(in Chinese)
殷亚楠. 铜对畜禽粪便堆肥过程中微生物群落及抗性基因影响机理研究[D]. 杨凌:西北农林科技大学, 2018:13 Yin Y N. Study on mechanism of effect of copper on microbial community and resistance genes in livestock manure composting process[D]. Yangling:Northwest A&F Univesity, 2018:13(in Chinese) Ji Y J, Ahn Y, Khare S, et al. An in vitro study to assess the impact of tetracycline on the human intestinal microbiome[J]. Anaerobe, 2018, 4(9):85-94 Leclercq S O, Wang C, Zhu Y, et al. Diversity of the tetracycline mobilome within a Chinese pig manure sample[J]. Applied and Environmental Microbiology, 2016, 82(21):1-16 Wang X, Chen Z, Jing K, et al. Removal of tetracycline by aerobic granular sludge and its bacterial community dynamics in SBR[J]. RSC Advances, 2018, 8(33):18284-18293 Liu X, Lv Y, Xu K, et al. Response of ginger growth to a tetracycline-contaminated environment and residues of antibiotic and antibiotic resistance genes[J]. Chemosphere, 2018, 201:137-143 Berendsen B J A, Lahr J, Nibbeling C, et al. The persistence of a broad range of antibiotics during calve, pig and broiler manure storage[J]. Chemosphere, 2018, 204:267-276 夏湘勤, 黄彩红, 席北斗, 等. 畜禽粪便中氟喹诺酮类抗生素的生物转化与机制研究进展[J]. 农业环境科学学报, 2019, 38(2):257-267 Xia X Q, Huang C H, Xi B D, et al. Review on biotransformation and mechanism of fluoroquinolone antibiotics from livestock manure[J]. Journal of Agro-Environment Science, 2019, 38(2):257-267(in Chinese)
王瑞, 魏源送. 畜禽粪便中残留四环素类抗生素和重金属的污染特征及其控制[J]. 农业环境科学学报, 2013, 9(9):1705-1719 Wang R, Wei Y S. Pollution and control of tetracyclines and heavy metals residues in animal manure[J]. Journal of Agro-Environment Science, 2013, 9(9):1705-1719(in Chinese)
杨晓芳, 杨涛, 王莹, 等. 四环素类抗生素污染现状及其环境行为研究进展[J]. 环境工程, 2014, 32(2):123-127 Yang X F, Yang T, Wang Y, et al. Research progress in pollution status and environmental behavior of tetracycline antibiotics[J]. Environmental Engineering, 2014, 32(2):123-127(in Chinese)
曾巧云, 丁丹, 檀笑. 中国农业土壤中四环素类抗生素污染现状及来源研究进展[J]. 生态环境学报, 2018, 27(9):1774-1782 Zeng Q Y, Ding D, Tan X. Pollution status and sources of tetracycline antibiotics in agricultural soil in China:A review[J]. Ecology and Environmental Sciences, 2018, 27(9):1774-1782(in Chinese)
李士俊, 谢文明. 污水处理厂中抗生素去除规律研究进展[J]. 环境科学与技术, 2019, 42(3):17-29 Li S J, Xie W M. Research advances in antibiotics removal in wastewater treatment plants:A review[J]. Environmental Science & Technology, 2019, 42(3):17-29(in Chinese)
孟丽华, 史艳伟, 时兵, 等. 四环素类抗生素残留的检测方法及其对渔业环境的影响研究进展[J]. 中国渔业质量与标准, 2017, 7(1):50-55 Meng L H, Shi Y W, Shi B, et al. Research progress of the detection method of tetracyclines antibiotics residues and its influence on fishery environment[J]. Chinese Fishery Quality and Standards, 2017, 7(1):50-55(in Chinese)
李宗宸, 魏群山, 罗专溪, 等. 九龙江沉积物主要组分对四环素类抗生素吸附性能对比[J]. 生态环境学报, 2016, 25(10):1714-1720 Li Z C, Wei Q S, Luo Z X, et al. Comparison of the performances of major components of the surface sediment from Jiulong River to tetracyclines adsorption[J]. Ecology and Environmental Sciences, 2016, 25(10):1714-1720(in Chinese)
陶美. 四环素降解菌筛选及其降解特性研究[D]. 成都:西南交通大学, 2018:12 Tao M. Tetracycline degrading bacteria screening and its degradation characteristics research[D]. Chengdu:Southwest Jiaotong University, 2018:12(in Chinese) Wexler P. TOXNET:The National Library of Medicine's toxicology database[J]. American Family Physician, 1995, 52(6):1677-1678 姚倩, 高玲琳, 姜亚磊, 等. 海南畜禽粪中四环素类和大环内酯类抗生素的含量及其分布特征[J]. 海南大学学报:自然科学版, 2017, 35(2):152-158 Yao Q, Gao L L, Jiang Y L, et al. Distribution characteristic of tetracycline and macrolide antibiotics contents in swine and chook manures of Hainan Province[J]. Journal of Hainan University:Natural Science, 2017, 35(2):152-158(in Chinese)
单英杰, 章明奎. 不同来源畜禽粪的养分和污染物组成[J]. 中国生态农业学报, 2012, 20(1):80-86 Shan Y J, Zhang M K. Contents of nutrient elements and pollutants in different sources of animal manures[J]. Chinese Journal of Eco-Agriculture, 2012, 20(1):80-86(in Chinese)
国彬, 姚丽贤, 刘忠珍, 等. 广州市兽用抗生素的环境残留研究[J]. 农业环境科学学报, 2011, 30(5):938-945 Guo B, Yao L X, Liu Z Z, et al. Environmental residues of veterinary antibiotics in Guangzhou City, China[J]. Journal of Agro-Environment Science, 2011, 30(5):938-945(in Chinese)
万位宁. 中国北方地区畜禽粪便以及周边土壤中典型抗生素残留及其污染特征研究[D]. 天津:南开大学, 2013:33 Wan W N. Study on typical antibiotic residues and their pollution characteristics in livestock manure and surrounding soil in northern China[D]. Tianjin:Nankai University, 2013:33(in Chinese) 任君焘, 徐琳. 山东东营地区畜禽粪便中抗生素残留研究[J]. 黑龙江畜牧兽医, 2019, 21(9):56-59 Ren J T, Xu L. Study on antibiotic residues in livestock manure in Dongying Area, Shandong[J]. Heilongjiang Animal Science and Veterinary Medicine, 2019, 21(9):56-59(in Chinese)
郭小夏, 刘洪涛, 常志州, 等. 有机废物好氧发酵腐殖质形成机理及农学效应研究进展[J]. 生态与农村环境学报, 2018, 34(6):489-498 Guo X X, Liu H T, Chang Z Z, et al. Review of humic substances developed in organic waste aerobic composting and its agronomic effect[J]. Journal of Ecology and Rural Environment, 2018, 34(6):489-498(in Chinese)
Mitchell S M, Ullman J L, Bary A, et al. Antibiotic degradation during thermophilic composting[J]. Water Air Soil Pollution, 2015, 226(2):1-13 张嘉超. 基于分子生物学的堆肥功能微生物种群与体系基质特性关系研究[D]. 长沙:湖南大学, 2013:100 Zhang J C. Study on the relationship between composting functional microbial population and system matrix properties based on molecular biology[D]. Changsha:Hunan University, 2013:100(in Chinese) 常会庆, 郑彩杰, 张建宇, 等. 不同环境温度条件对脱水污泥堆肥效果的影响研究[J]. 生态环境学报, 2017, 26(10):1755-1760 Chang H Q, Zheng C J, Zhang J Y, et al. Effects of different environmental temperature on dewatered sludge composting[J]. Ecology and Environmental Sciences, 2017, 26(10):1755-1760(in Chinese)
Huang X, Zheng J L, Tian S H. Higher temperatures do not always achieve better antibiotic resistance genes removal in anaerobic digestion of swine manure[J]. Applied and Environmental Microbiology, 2019, 22(3):1-12 储意轩, 汪华, 方程冉, 等. 畜禽粪便中残留抗生素污染特征及其生物降解的研究进展[J]. 科技通报, 2018, 34(11):16-23 Chu Y X, Wang H, Fang C R, et al. Research progress of the pollution characteristics and biodegradation of antibiotics residues in livestock and poultry feces[J]. Bulletin of Science and Technology, 2018, 34(11):16-23(in Chinese)
付祥峰, 刘琪琪, 李恋卿, 等. 生物质炭对猪粪堆肥过程中氮素转化及温室气体排放的影响[J]. 农业环境科学学报, 2017, 36(9):1893-1900 Fu X F, Liu Q Q, Li L Q, et al. Effects of biochar on nitrogen transformation and greenhouse gas emissions during swine manure composting[J]. Journal of Agro-Environment Science, 2017, 36(9):1893-1900(in Chinese)
秦莉, 沈玉君, 李国学, 等. 不同C/N比对堆肥腐熟度和含氮气体排放变化的影响[J]. 农业环境科学学报, 2009, 28(12):2668-2673 Qin L, Shen Y J, Li G X, et al. The impact of composting with different C/N on maturity variation and emission of gas concluding N[J]. Journal of Agro-Environment Science, 2009, 28(12):2668-2673(in Chinese)
周思, 刘永霞, 葛永怡. 碳氮比对猪粪堆肥腐熟度的影响[J]. 贵州农业科学, 2017, 45(9):65-68 Zhou S, Liu Y X, Ge Y Y. Effects of carbon-nitrogen ratio on pig manure composting maturity[J]. Guizhou Agricultural Science, 2017, 45(9):65-68(in Chinese)
Chu Y, Fang C, Wang H, et al. Effects of anaerobic composting on tetracycline degradation in swine manure[J]. Chinese Journal of Chemical Engineering, 2017, 25(10):1505-1511 Wu X, Wei Y, Zheng J, et al. The behavior of tetracyclines and their degradation products during swine manure composting[J]. Bioresource Technology, 2011, 102(10):5924-5931 勾长龙, 王雨琼, 张喜庆, 等. 高温堆肥对猪粪中四环素类抗生素及抗性基因的影响[J]. 环境科学学报, 2017, 37(4):1454-1460 Gou C L, Wang Y Q, Zhang X Q, et al. Effects of high-temperature composting on tetracyclines and tetracycline resistance genes in swine manure[J]. Acta Scientiae Circumstantiae, 2017, 37(4):1454-1460(in Chinese)
肖礼, 黄懿梅, 赵俊峰, 等. 外源菌剂对猪粪堆肥质量及四环素类抗生素降解的影响[J]. 农业环境科学学报, 2016, 35(1):172-178 Xiao L, Huang Y M, Zhao J F, et al. Effects of exogenous microbial agents on pig manure compost quality and tetracycline antibiotic degradation[J]. Journal of Agro-Environment Science, 2016, 35(1):172-178(in Chinese)
Huang G F, Wong J W C, Wu Q T, et al. Effect of C/N on composting of pig manure with sawdust[J]. Waste Management, 2004, 24(8):805-813 Li S, Li D, Li J, et al. Effect of spent mushroom substrate as a bulking agent on gaseous emissions and compost quality during pig manure composting[J]. Environmental Science and Pollution Research, 2018, 25(13):12398-12406 金珠理达, 王顺利, 邹荣松, 等. 猪粪堆肥快速发酵菌剂及工艺控制参数初步研究[J]. 农业环境科学学报, 2010, 29(3):586-591 Jin Z L D, Wang S L, Zou R S, et al. Microbial agents and the optimum control parameters for pig manure composting[J]. Journal of Agro-Environment Science, 2010, 29(3):586-591(in Chinese)
李荣华, 张广杰, 秦睿, 等. 添加钝化剂对猪粪好氧堆肥过程中理化特性的影响[J]. 环境科学学报, 2012, 32(10):2591-2599 Li R H, Zhang G J, Qin R, et al. Influence of heavy metal passive agents on the compost physicochemical properties during the swine manure composting[J]. Acta Scientiae Circumstantiae, 2012, 32(10):2591-2599(in Chinese)
Li Y, Luo W, Li G, et al. Performance of phosphogypsum and calcium magnesium phosphate fertilizer for nitrogen conservation in pig manure composting[J]. Bioresource Technology, 2018, 18(2):53-59 Zhou J M, Wang L T, Wang H M, et al. Effects of different ratios of pig manure to fungus residue on physicochemical parameters during composting[J]. Journal of the Air & Waste Management Association, 2016, 11(4):499-507 罗义, 周启星. 抗生素抗性基因(ARGs)——一种新型环境污染物[J]. 环境科学学报, 2008, 28(8):1499-1505 Luo Y, Zhou Q X. Antibiotic resistance genes (ARGs) as emerging pollutants[J]. Acta Scientiae Circumstantiae, 2008, 28(8):1499-1505(in Chinese)
邹威, 罗义, 周启星. 畜禽粪便中抗生素抗性基因(ARGs)污染问题及环境调控[J]. 农业环境科学学报, 2014, 33(12):2281-2287 Zou W, Luo Y, Zhou Q X. Pollution and environmental regulation of antibiotic resistance genes (ARGs) in livestock manure[J]. Journal of Agro-Environment Science, 2014, 33(12):2281-2287(in Chinese)
王冉, 刘铁铮, 王恬. 抗生素在环境中的转归及其生态毒性[J]. 生态学报, 2006, 26(1):265-270 Wang R, Liu T Z, Wang T. The fate of antibiotics in environment and its ecotoxicology:A review[J]. Acta Ecologica Sinica, 2006, 26(1):265-270(in Chinese)
Huang L, Xu Y B, Xu J X, et al. Dissemination of antibiotic resistance genes (ARGs) by rainfall on a cyclic economic breeding livestock farm[J]. International Biodeterioration & Biodegradation, 2019, 138:114-121 Wang H, Fang C, Wang Q, et al. Sorption of tetracycline on biochar derived from rice straw and swine manure[J]. RSC Advances, 2018, 8(29):16260-16268 陈琳琳, 李宝泉. 新型抗生素抗性基因传播元件ISCR及其生态风险[J]. 应用生态学报, 2015, 26(10):3215-3225 Chen L L, Li B Q. Novel transmission element of antibiotic resistance genes ISCR and its ecological risk[J]. Chinese Journal of Applied Ecology, 2015, 26(10):3215-3225(in Chinese)
Li M F, Liu Y G, Zeng G M, et al. Tetracycline absorbed onto nitrilotriacetic acid-functionalized magnetic graphene oxide:Influencing factors and uptake mechanism[J]. Journal of Colloid and Interface Science, 2016, 485:269-279 陈琨, 黄东萍. 各种吸附材料在去除水中四环素类抗生素残留的应用[J]. 广西医科大学学报, 2018, 15(8):1169-1172 李霞, 邓立刚, 王峰恩, 等. 堆肥消减畜禽粪便中病原微生物及抗生素残留的研究进展[J]. 山东农业科学, 2017, 49(7):161-166 Li X, Deng L G, Wang F E, et al. Progress in removal effect of composting on residues of pathogenic microorganisms and antibiotics in livestock and poultry manure[J]. Shandong Agricultural Science, 2017, 49(7):161-166(in Chinese)
楼晨露. 长期定量施用猪粪稻田土壤中典型抗生素及其抗性基因污染研究[D]. 杭州:浙江大学, 2016:32 Lou C L. Study on the pollution of typical antibiotics and their resistance genes in long-term quantitative application of pig manure paddy soil[D]. Hangzhou:Zhejiang University, 2016:32(in Chinese) Guo T, Lou C, Zhai W, et al. Increased occurrence of heavy metals, antibiotics and resistance genes in surface soil after long-term application of manure[J]. Science of the Total Environment, 2018, 635:995-1003 张凯煜. 土霉素和磺胺二甲嘧啶对堆肥过程中微生物群落多样性及抗性基因的影响[D]. 杨凌:西北农林科技大学, 2015:20 Zhang K Y. Effects of oxytetracycline and sulfamethazine on microbial community diversity and resistance genes during composting[D]. Yangling:Northwest A&F Univesity, 2015:20(in Chinese) 时红蕾. 粪便好氧堆肥过程中典型抗生素的行为特性研究[D]. 西安:西安建筑科技大学, 2018:85 Shi H L. Study on behavioral characteristics of typical antibiotics in fecal aerobic composting[D]. Xi'an:Xi'an University of Architecture and Technology, 2018:85(in Chinese) 马骏. 四环素在堆肥过程中的降解及其对堆肥中微生物群落功能多样性的影响[D]. 杨凌:西北农林科技大学, 2016:21 Ma J. Degradation of tetracycline during composting and its effect on microbial community functional diversity in compost[D]. Yangling:Northwest A&F Univesity, 2016:21(in Chinese) 王晓慧, 张明, 任雪丽, 等. 四环素耐药基因在猪粪便、堆肥和土壤中的归趋[J]. 安徽农学通报, 2017, 23(9):22-23 Wang X H, Zhang M, Ren X L, et al. Transport and fate of tetracycline resistance genes in pig manure, compost and soil[J]. Anhui Agricultural Science Bulletin, 2017, 23(9):22-23(in Chinese)
李海超. 生物炭对堆肥过程中微生物群落多样性及抗生素抗性基因的影响[D]. 杨凌:西北农林科技大学, 2017:31 Li H C. Effects of biochar on microbial community diversity and antibiotic resistance genes during composting[D]. Yangling:Northwest A&F Univesity, 2017:31(in Chinese) Kang Y, Li Q, Xia D, et al. Short-term thermophilic treatment cannot remove tetracycline resistance genes in pig manures but exhibits controlling effects on their accumulation and spread in soil[J]. Journal of Hazardous Materials, 2017, 340:213-220 Zhang J, Lin H, Ma J W, et al. Compost-bulking agents reduce the reservoir of antibiotics and antibiotic resistance genes in manures by modifying bacterial microbiota[J]. Science of the Total Environment, 2019, 649:396-404 Cheng D, Feng Y, Liu Y, et al. Dynamics of oxytetracycline, sulfamerazine, and ciprofloxacin and related antibiotic resistance genes during swine manure composting[J]. Journal of Environmental Management, 2019, 230:102-109 Mao H, Lv Z, Sun H, et al. Improvement of biochar and bacterial powder addition on gaseous emission and bacterial community in pig manure compost[J]. Bioresource Technology, 2018, 258:195-202 刘元望, 李兆君, 冯瑶, 等. 微生物降解抗生素的研究进展[J]. 农业环境科学学报, 2016, 35(2):212-224 Liu Y W, Li Z J, Feng Y, et al. Research progress in microbial degradation of antibiotics[J]. Journal of Agro-Environment Science, 2016, 35(2):212-224(in Chinese)
黄雅楠, 王晓慧, 张明, 等. 高通量测序技术分析猪粪堆肥过程中微生物群落结构变化[J]. 微生物学杂志, 2018, 38(5):27-32 Huang Y N, Wang X H, Zhang M, et al. Analysis of microbial community changes in pig excrement during compost process based on high-throughput sequencing technology[J]. Journal of Microbiology, 2018, 38(5):27-32(in Chinese)
曹云, 常志州, 黄红英, 等. 畜禽粪便堆肥前期理化及微生物性状研究[J]. 农业环境科学学报, 2015, 34(11):2198-2207 Cao Y, Chang Z Z, Huang H Y, et al. Chemical and biological changes during early stage of composting of different animal wastes[J]. Journal of Agro-Environment Science, 2015, 34(11):2198-2207(in Chinese)
张海滨, 孟海波, 沈玉君, 等. 好氧堆肥微生物研究进展[J]. 中国农业科技导报, 2017, 19(3):1-8 Zhang H B, Meng H B, Shen Y J, et al. Research progress on microbial aerobic composting[J]. Journal of Agricultural Science and Technology, 2017, 19(3):1-8(in Chinese)
毛薇, 吴画斌. 规模化畜禽养殖废弃物循环利用模式及实施路径[J]. 中国畜牧杂志, 2016, 52(6):71-74 Mao W, Wu H B. Waste recycling mode and implementation path of large-scale livestock and poultry breeding[J]. Chinese Journal of Animal Science, 2016, 52(6):71-74(in Chinese)
李伟明, 鲍艳宇, 周启星. 四环素类抗生素降解途径及其主要降解产物研究进展[J]. 应用生态学报, 2012, 23(8):2300-2308 Li W M, Bao Y Y, Zhou Q X. Degradation pathways and main degradation products of tetracycline antibiotics:Research progress[J]. Chinese Journal of Applied Ecology, 2012, 23(8):2300-2308(in Chinese)
Winckler C, Grafe A. Use of veterinary drugs in intensive animal production[J]. Journal of Soils and Sediments, 2001, 1(2):66-70 吴伯清. 畜禽养殖废弃物无害化资源利用模式[J]. 中国畜禽种业, 2019, 15(7):66 潘寻, 强志民, 贲伟伟. 高温堆肥对猪粪中多类抗生素的去除效果[J]. 生态与农村环境学报, 2013, 29(1):64-69 Pan X, Qiang Z M, Ben W W. Removal of antibiotics from pig manure by high temperature composting[J]. Journal of Ecology and Rural Environment, 2013, 29(1):64-69(in Chinese)
Wu X, Wei Y, Zheng J, et al. The behavior of tetracyclines and their degradation products during swine manure composting[J]. Bioresource Technology, 2011, 102(10):5924-5931 Chai R S, Huang L D, Li L L, et al. Degradation of tetracyclines in pig manure by composting with rice straw[J]. International Journal of Environmental Research & Public Health, 2016, 13(3):1-9 童子林, 刘元璐, 胡真虎, 等. 四环素类抗生素污染畜禽粪便的厌氧消化特征[J]. 环境科学, 2012, 33(3):1028-1032 Tong Z L, Liu Y L, Hu Z H, et al. Anaerobic digestion of animal manure contaminated by tetracyclines[J]. Environmental Science, 2012, 33(3):1028-1032(in Chinese)
Chu Y, Fang C, Wang H, et al. Effects of anaerobic composting on tetracycline degradation in swine manure[J]. Chinese Journal of Chemical Engineering, 2017, 25(10):1505-1511 Wang C, Dong D, Strong P J, et al. Microbial phylogeny determines transcriptional response of resistome to dynamic composting processes[J]. Microbiome, 2017, 5(1):1-15 成洁, 杜慧玲, 张天宝, 等. 四环素类抗生素降解菌的分离与鉴定[J]. 核农学报, 2017, 31(5):884-888 Cheng J, Du H L, Zhang T B, et al. Isolation and identification of tetracyclines degrading bacteria[J]. Journal of Nuclear Agricultural Sciences, 2017, 31(5):884-888(in Chinese)
吴学玲, 吴晓燕, 李交昆, 等. 一株四环素高效降解菌的分离及降解特性[J]. 生物技术通报, 2018, 34(5):172-178 Wu X L, Wu X Y, Li J K, et al. Isolation and degradation characteristics of a efficient tetracycline-degrading strain[J]. Biotechnology Bulletin, 2018, 34(5):172-178(in Chinese)
Liu X, Lv Y, Xu K, et al. Response of ginger growth to a tetracycline-contaminated environment and residues of antibiotic and antibiotic resistance genes[J]. Chemosphee, 2018, 17(2):137-201 王攀攀, 袁巧霞, 周文兵, 等. 光催化降解沼液中四环素类抗生素效果及反应动力学研究[J]. 农业工程学报, 2018, 34(23):201-206 Wang P P, Yuan Q X, Zhou W B, et al. Study on photocatalytic degradation and reaction kinetics of tetracycline antibiotics in biogas slurry[J]. Transactions of the Chinese Society of Agricultural Engineering, 2018, 34(23):201-206(in Chinese)
Wu J, Zhang A, Li G, et al. Impact of phosphate additive on organic carbon component degradation during pig manure composting[J]. Environmental Science and Pollution Research, 2019, 27(2):11805-11814 Wang H, Fang C, Wang Q, et al. Sorption of tetracycline on biochar derived from rice straw and swine manure[J]. RSC Advances, 2018, 8(29):16260-16268 Khan M H, Bae H, Jung J Y. Tetracycline degradation by ozonation in the aqueous phase:Proposed degradation intermediates and pathway[J]. Journal of Hazardous Materials, 2010, 18(1):659-665 -
点击查看大图
计量
- 文章访问数: 3241
- HTML全文浏览数: 3241
- PDF下载数: 92
- 施引文献: 0
下载:
