2020 Volume 15 Issue 6
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Wang Shuang, Lu Zhen, Li Fei, Cong Ming, Ji Chenglong, Wu Huifeng. A Review of Pollution Status and Toxicological Researches of Typical Brominated Flame Retardants Tetrabromobisphenol A (TBBPA) and Decabromodiphenyl Ethane (DBDPE)[J]. Asian Journal of Ecotoxicology, 2020, 15(6): 24-42. doi: 10.7524/AJE.1673-5897.20190804003
Citation: Wang Shuang, Lu Zhen, Li Fei, Cong Ming, Ji Chenglong, Wu Huifeng. A Review of Pollution Status and Toxicological Researches of Typical Brominated Flame Retardants Tetrabromobisphenol A (TBBPA) and Decabromodiphenyl Ethane (DBDPE)[J]. Asian Journal of Ecotoxicology, 2020, 15(6): 24-42. doi: 10.7524/AJE.1673-5897.20190804003
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A Review of Pollution Status and Toxicological Researches of Typical Brominated Flame Retardants Tetrabromobisphenol A (TBBPA) and Decabromodiphenyl Ethane (DBDPE)

  • 1. CAS Key Laboratory of Coastal Environmental Processes and Ecological Remediation, Shandong Key Laboratory of Coastal Environmental Processes, Yantai Institute of Coastal Zone Research(YIC), Chinese Academy of Sciences(CAS), Yantai 264003, China;

  • 2. Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266237, China;

  • 3. University of Chinese Academy of Sciences, Beijing 100049, China

  • Corresponding author: Wu Huifeng, hfwu@yic.ac.cn
  • Received Date: 04/08/2019
    Fund Project:
  • With hexabromocyclododecane (HBCDs) and poly brominated diphenyl ethers (PBDEs) listed as persistent organic pollutants (POPs), tetrabromobisphenol A (TBBPA) and decabromodiphenyl ethane (DBDPE) have become two of the most widely produced and used brominated flame retardants (BFRs). The underlying ecological risk of TBBPA and DBDPE have received increasing attentions since these two typical BFRs are being detected at high concentrations in environmental media. This paper summarized the pollution status of TBBPA and DBDPE and their toxicological effects. TBBPA and DBDPE have been detected in multiple environmental media, such as atmosphere, waters, soil, sediment and organisms. In addition, more severe pollution could be found in industrial areas. TBBPA and DBDPE were even found in human body and breast milk. Overall, TBBPA presented developmental toxicity, hepatorenal toxicity, endocrine disruption effect, reproductive toxicity, and neurotoxicity, while DBDPE showed developmental toxicity, hepatorenal toxicity, and endocrine disruption effect. According to the limited reports on DBDPE toxicity, we concluded that DBDPE was of relatively low toxicity. The aim of this review is to help evaluate the environmental risk, analyze the environmental capacity, and governmentally control the production of TBBPA and DBDPE.
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A Review of Pollution Status and Toxicological Researches of Typical Brominated Flame Retardants Tetrabromobisphenol A (TBBPA) and Decabromodiphenyl Ethane (DBDPE)

  • Received Date: 04/08/2019
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Abstract: With hexabromocyclododecane (HBCDs) and poly brominated diphenyl ethers (PBDEs) listed as persistent organic pollutants (POPs), tetrabromobisphenol A (TBBPA) and decabromodiphenyl ethane (DBDPE) have become two of the most widely produced and used brominated flame retardants (BFRs). The underlying ecological risk of TBBPA and DBDPE have received increasing attentions since these two typical BFRs are being detected at high concentrations in environmental media. This paper summarized the pollution status of TBBPA and DBDPE and their toxicological effects. TBBPA and DBDPE have been detected in multiple environmental media, such as atmosphere, waters, soil, sediment and organisms. In addition, more severe pollution could be found in industrial areas. TBBPA and DBDPE were even found in human body and breast milk. Overall, TBBPA presented developmental toxicity, hepatorenal toxicity, endocrine disruption effect, reproductive toxicity, and neurotoxicity, while DBDPE showed developmental toxicity, hepatorenal toxicity, and endocrine disruption effect. According to the limited reports on DBDPE toxicity, we concluded that DBDPE was of relatively low toxicity. The aim of this review is to help evaluate the environmental risk, analyze the environmental capacity, and governmentally control the production of TBBPA and DBDPE.

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