空气微塑料的分布特征、暴露评估及毒性效应
Distribution Characteristics, Exposure Assessment and Toxic Effects of Airborne Microplastics
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摘要: 微塑料现普遍被定义为环境中尺寸<5 mm的塑料颗粒,是一种广泛存在于人们生活环境和自然环境中的新型污染物。研究人员在空气、水体和土壤等各种自然环境介质以及鱼虾、贻贝类、家禽甚至人体肺组织、人体粪便等多种生物样本中均已发现微塑料的存在。由于尺寸微小,空气微塑料可通过呼吸过程被机体吸入并沉积在体内。本文综述了现阶段空气微塑料的来源、分布特征、暴露评估及其毒性效应等最新研究进展,分析了室内外以及城乡地区空气微塑料的丰度、形状、粒径分布及组分类型等分布特征,并对微塑料吸入毒性效应及其复合毒性效应进行综述和分析,同时展望今后研究中需完善和规范空气微塑料的检测分析方法、进一步研究和揭示空气微塑料人体暴露特征及其健康风险等。Abstract: Microplastics are generally defined as plastic particles with a size of <5 mm in the environment. It is a new pollutant which widely exist in our living environment and natural environment. Researchers have found the existence of microplastics in various natural environmental media such as air, water, soil, fish and shrimp, mussels, poultry, human lung tissue, human feces and other biological samples. Due to their small size, airborne microplastics can be inhaled and deposited in the body through the process of breathing. We reviewed the latest research progress on the sources, distribution characteristics, exposure assessment and toxic effects of airborne microplastics at this stage, summarizes and analyzes the inhalation toxic effects of microplastics and their composite toxic effects. It is expected to improve and standardize the detection and analysis methods of air microplastics in the future research, to reveal the human exposure characteristics and health risks of air microplastics.
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王菡娟. "塑"尽其用须速办[N]. 人民政协报, 2021-07-22(5) 陈婉. 塑料污染治理需协同多方力量共同行动[J]. 环境经济, 2020(19):28-31 Amato-Lourenço L F, Dos Santos Galvão L, de Weger L A, et al. An emerging class of air pollutants:Potential effects of microplastics to respiratory human health?[J]. The Science of the Total Environment, 2020, 749:141676 Lau W W Y, Shiran Y, Bailey R M, et al. Evaluating scenarios toward zero plastic pollution[J]. Science, 2020, 369(6510):1455-1461 Pironti C, Ricciardi M, Motta O, et al. Microplastics in the environment:Intake through the food web, human exposure and toxicological effects[J]. Toxics, 2021, 9(9):224 Facciolà A, Visalli G, Pruiti Ciarello M, et al. Newly emerging airborne pollutants:Current knowledge of health impact of micro and nanoplastics[J]. International Journal of Environmental Research and Public Health, 2021, 18(6):2997 Rhodes C J. Solving the plastic problem:From cradle to grave, to reincarnation[J]. Science Progress, 2019, 102(3):218-248 Frias J P G L, Otero V, Sobral P. Evidence of microplastics in samples of zooplankton from Portuguese coastal waters[J]. Marine Environmental Research, 2014, 95:89-95 Bellas J, Martínez-Armental J, Martínez-Cámara A, et al. Ingestion of microplastics by demersal fish from the Spanish Atlantic and Mediterranean coasts[J]. Marine Pollution Bulletin, 2016, 109(1):55-60 Amato-Lourenço L F, Carvalho-Oliveira R, Júnior G R, et al. Presence of airborne microplastics in human lung tissue[J]. Journal of Hazardous Materials, 2021, 416:126124 Schwabl P, K ppel S, K nigshofer P, et al. Detection of various microplastics in human stool:A prospective case series[J]. Annals of Internal Medicine, 2019, 171(7):453-457 Ragusa A, Svelato A, Santacroce C, et al. Plasticenta:First evidence of microplastics in human placenta[J]. Environment International, 2021, 146:106274 Braun T, Ehrlich L, Henrich W, et al. Detection of microplastic in human placenta and meconium in a clinical setting[J]. Pharmaceutics, 2021, 13(7):921 Ibrahim Y S, Tuan Anuar S, Azmi A A, et al. Detection of microplastics in human colectomy specimens[J]. JGH Open:An Open Access Journal of Gastroenterology and Hepatology, 2020, 5(1):116-121 Liu K, Wang X H, Fang T, et al. Source and potential risk assessment of suspended atmospheric microplastics in Shanghai[J]. The Science of the Total Environment, 2019, 675:462-471 Liao Z L, Ji X L, Ma Y, et al. Airborne microplastics in indoor and outdoor environments of a coastal city in Eastern China[J]. Journal of Hazardous Materials, 2021, 417:126007 Jenner L C, Sadofsky L R, Danopoulos E, et al. Household indoor microplastics within the Humber region (United Kingdom):Quantification and chemical characterisation of particles present[J]. Atmospheric Environment, 2021, 259:118512 van Wezel A, Caris I, Kools S A E. Release of primary microplastics from consumer products to wastewater in the Netherlands[J]. Environmental Toxicology and Chemistry, 2016, 35(7):1627-1631 Barboza L G A, Gimenez B. Microplastics in the marine environment:Current trends and future perspectives[J]. Marine Pollution Bulletin, 2015, 97(1-2):5-12 Loppi S, Roblin B, Paoli L, et al. Accumulation of airborne microplastics in lichens from a landfill dumping site (Italy)[J]. Scientific Reports, 2021, 11(1):4564 Kole P J, L hr A J, van Belleghem F, et al. Wear and tear of tyres:A stealthy source of microplastics in the environment[J]. International Journal of Environmental Research and Public Health, 2017, 14(10):1265 O'Brien S, Okoffo E D, Rauert C, et al. Quantification of selected microplastics in Australian urban road dust[J]. Journal of Hazardous Materials, 2021, 416:125811 Klein M, Fischer E K. Microplastic abundance in atmospheric deposition within the Metropolitan area of Hamburg, Germany[J]. Science of the Total Environment, 2019, 685:96-103 Liu C G, Li J, Zhang Y, et al. Widespread distribution of PET and PC microplastics in dust in urban China and their estimated human exposure[J]. Environment International, 2019, 128:116-124 O'Brien S, Okoffo E D, O'Brien J W, et al. Airborne emissions of microplastic fibres from domestic laundry dryers[J]. The Science of the Total Environment, 2020, 747:141175 Ma J, Chen F Y, Xu H, et al. Face masks as a source of nanoplastics and microplastics in the environment:Quantification, characterization, and potential for bioaccumulation[J]. Environmental Pollution, 2021, 288:117748 Zhang J J, Wang L, Kannan K. Microplastics in house dust from 12 countries and associated human exposure[J]. Environment International, 2020, 134:105314 Zhu X, Huang W, Fang M Z, et al. Airborne microplastic concentrations in five megacities of northern and southeast China[J]. Environmental Science & Technology, 2021, 55(19):12871-12881 Yukioka S, Tanaka S, Nabetani Y, et al. Occurrence and characteristics of microplastics in surface road dust in Kusatsu (Japan), Da Nang (Vietnam), and Kathmandu (Nepal)[J]. Environmental Pollution, 2020, 256:113447 Gaston E, Woo M, Steele C, et al. Microplastics differ between indoor and outdoor air masses:Insights from multiple microscopy methodologies[J]. Applied Spectroscopy, 2020, 74(9):1079-1098 Wright S L, Ulke J, Font A, et al. Atmospheric microplastic deposition in an urban environment and an evaluation of transport[J]. Environment International, 2020, 136:105411 Cai L Q, Wang J D, Peng J P, et al. Characteristic of microplastics in the atmospheric fallout from Dongguan City, China:Preliminary research and first evidence[J]. Environmental Science and Pollution Research International, 2017, 24(32):24928-24935 周帅, 李伟轩, 唐振平, 等. 气载微塑料的赋存特征、迁移规律与毒性效应研究进展[J]. 中国环境科学, 2020, 40(11):5027-5037 Zhou S, Li W X, Tang Z P, et al. Progress on the occurrence, migration and toxicity of airborne microplastics[J]. China Environmental Science, 2020, 40(11):5027-5037(in Chinese)
Dris R, Gasperi J, Saad M, et al. Synthetic fibers in atmospheric fallout:A source of microplastics in the environment?[J]. Marine Pollution Bulletin, 2016, 104(1-2):290-293 Soltani N S, Taylor M P, Wilson S P. Quantification and exposure assessment of microplastics in Australian indoor house dust[J]. Environmental Pollution, 2021, 283:117064 Wang X H, Li C, Liu K, et al. Atmospheric microplastic over the South China Sea and East Indian Ocean:Abundance, distribution and source[J]. Journal of Hazardous Materials, 2020, 389:121846 田媛, 涂晨, 周倩, 等. 环渤海海岸大气微塑料污染时空分布特征与表面形貌[J]. 环境科学学报, 2020, 40(4):1401-1409 Tian Y, Tu C, Zhou Q, et al. The temporal and spatial distribution and surface morphology of atmospheric microplastics around the Bohai Sea[J]. Acta Scientiae Circumstantiae, 2020, 40(4):1401-1409(in Chinese)
涂晨, 田媛, 刘颖, 等. 大连海岸带夏、秋季大气沉降(微)塑料的赋存特征及其表面生物膜特性[J]. 环境科学, 2022, 43(4):1821-1828 Tu C, Tian Y, Liu Y, et al. Occurrence of atmospheric (micro)plastics and the characteristics of the plastic associated biofilms in the coastal zone of Dalian in summer and autumn[J]. Environmental Science, 2022, 43(4):1821-1828(in Chinese)
Pauly J L, Stegmeier S J, Allaart H A, et al. Inhaled cellulosic and plastic fibers found in human lung tissue[J]. Cancer Epidemiology, Biomarkers & Prevention:A Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 1998, 7(5):419-428 王英雪, 徐熳, 王立新, 等. 微塑料在哺乳动物的暴露途径、毒性效应和毒性机制浅述[J]. 环境化学, 2021, 40(1):41-54 Wang Y X, Xu M, Wang L X, et al. The exposure routes, organ damage and related mechanism of the microplastics on the mammal[J]. Environmental Chemistry, 2021, 40(1):41-54(in Chinese)
Vianello A, Jensen R L, Liu L, et al. Simulating human exposure to indoor airborne microplastics using a Breathing Thermal Manikin[J]. Scientific Reports, 2019, 9:8670 那军, 耿译航, 蒋莹, 等. 快递员痰液和鼻腔冲洗液中微塑料污染分析[J]. 中国公共卫生, 2021, 37(3):451-454 Na J, Geng Y H, Jiang Y, et al. Microplastics detected in sputum and nasal lavage fluid of couriers:A pilot study[J]. Chinese Journal of Public Health, 2021, 37(3):451-454(in Chinese)
Gasperi J, Stephanie L W, Rachid D, et al. Microplastics in air:Are we breathing it in?[J]. Current Opinion in Environmental Science & Health, 2018, 1:1-5 郭西龙. 颗粒物在人体肺部沉积规律及影响因素研究[D]. 长沙:中南大学, 2013:22-23 Guo X L. Particle deposition in human lungs:Mechanisms and factors[D]. Changsha:Central South University, 2013:22 -23(in Chinese)
Carvalho T C, Peters J I, Williams III R O. Influence of particle size on regional lung deposition-What evidence is there?[J]. International Journal of Pharmaceutics, 2011, 406(1-2):1-10 Xu M K, Gulinare H, Qianru Z, et al. Internalization and toxicity:A preliminary study of effects of nanoplastic particles on human lung epithelial cell[J]. Science of the Total Environment, 2019, 694:133794 Pauluhn J. Poorly soluble particulates:Searching for a unifying denominator of nanoparticles and fine particles for DNEL estimation[J]. Toxicology, 2011, 279(1-3):176-188 H Greim P B. Toxicity of fibers and particles-Report of the workshop held in Munich, Germany, 26-27 October 2000[J]. Inhalation Toxicology, 2001, 13(9):737-754 Geiser M, Kreyling W G. Deposition and biokinetics of inhaled nanoparticles[J]. Particle and Fibre Toxicology, 2010, 7:2 Goodman K E, Hare J T, Khamis Z I, et al. Exposure of human lung cells to polystyrene microplastics significantly retards cell proliferation and triggers morphological changes[J]. Chemical Research in Toxicology, 2021, 34(4):1069-1081 Dong C D, Chen C W, Chen Y C, et al. Polystyrene microplastic particles:In vitro pulmonary toxicity assessment[J]. Journal of Hazardous Materials, 2020, 385:121575 Chiu H W, Xia T, Lee Y H, et al. Cationic polystyrene nanospheres induce autophagic cell death through the induction of endoplasmic reticulum stress[J]. Nanoscale, 2015, 7(2):736-746 Paget V, Dekali S, Kortulewski T, et al. Specific uptake and genotoxicity induced by polystyrene nanobeads with distinct surface chemistry on human lung epithelial cells and macrophages[J]. PLoS One, 2015, 10(4):e0123297 Wu B, Wu X, Liu S, et al. Size-dependent effects of polystyrene microplastics on cytotoxicity and efflux pump inhibition in human Caco-2 cells[J]. Chemosphere, 2019, 221:333-341 Xu M K, Halimu G, Zhang Q R, et al. Internalization and toxicity:A preliminary study of effects of nanoplastic particles on human lung epithelial cell[J]. The Science of the Total Environment, 2019, 694:133794 Prata J C. Airborne microplastics:Consequences to human health?[J]. Environmental Pollution, 2018, 234:115-126 Mastrangelo G, Fedeli U, Fadda E, et al. Lung cancer risk in workers exposed to poly(vinyl chloride) dust:A nested case-referent study[J]. Occupational and Environmental Medicine, 2003, 60(6):423-428 Anyfantis I D, Rachiotis G, Hadjichristodoulou C, et al. Respiratory symptoms and lung function among Greek cotton industry workers:A cross-sectional study[J]. The International Journal of Occupational and Environmental Medicine, 2017, 8(1):32-38 Song Y, Li X, Du X. Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma[J]. The European Respiratory Journal, 2009, 34(3):559-567 Oo T W, Thandar M, Htun Y M, et al. Assessment of respiratory dust exposure and lung functions among workers in textile mill (Thamine), Myanmar:A cross-sectional study[J]. BMC Public Health, 2021, 21(1):673 Braun T, Ehrlich L, Henrich W, et al. Detection of microplastic in human placenta and meconium in a clinical setting[J]. Pharmaceutics, 2021, 13(7):921 Fournier S B, D'Errico J N, Adler D S, et al. Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy[J]. Particle and Fibre Toxicology, 2020, 17(1):55 Hu J N, Qin X L, Zhang J W, et al. Polystyrene microplastics disturb maternal-fetal immune balance and cause reproductive toxicity in pregnant mice[J]. Reproductive Toxicology, 2021, 106:42-50 Hou J Y, Lei Z M, Cui L L, et al. Polystyrene microplastics lead to pyroptosis and apoptosis of ovarian granulosa cells via NLRP3/Caspase-1 signaling pathway in rats[J]. Ecotoxicology and Environmental Safety, 2021, 212:112012 Li S D, Wang Q M, Yu H, et al. Polystyrene microplastics induce blood-testis barrier disruption regulated by the MAPK-Nrf2 signaling pathway in rats[J]. Environmental Science and Pollution Research International, 2021, 28(35):47921-47931 Kwon W, Kim D, Kim H Y, et al. Microglial phagocytosis of polystyrene microplastics results in immune alteration and apoptosis in vitro and in vivo[J]. The Science of the Total Environment, 2022, 807(Pt 2):150817 Lu L, Wan Z Q, Luo T, et al. Polystyrene microplastics induce gut microbiota dysbiosis and hepatic lipid metabolism disorder in mice[J]. The Science of the Total Environment, 2018, 631-632:449-458 Deng Y F, Zhang Y, Lemos B, et al. Tissue accumulation of microplastics in mice and biomarker responses suggest widespread health risks of exposure[J]. Scientific Reports, 2017, 7:46687 Barhoumi B, Tedetti M, Heimbürger-Boavida L E, et al. Chemical composition and in vitro aryl hydrocarbon receptor-mediated activity of atmospheric particulate matter at an urban, agricultural and industrial site in North Africa (Bizerte, Tunisia)[J]. Chemosphere, 2020, 258:127312 Borges-Ramírez M M, Escalona-Segura G, Huerta-Lwanga E, et al. Organochlorine pesticides, polycyclic aromatic hydrocarbons, metals and metalloids in microplastics found in regurgitated pellets of black vulture from Campeche, Mexico[J]. The Science of the Total Environment, 2021, 801:149674 Menéndez-Pedriza A, Jaumot J, Bedia C. Lipidomic analysis of single and combined effects of polyethylene microplastics and polychlorinated biphenyls on human hepatoma cells[J]. Journal of Hazardous Materials, 2022, 421:126777 Sharma M D, Elanjickal A I, Mankar J S, et al. Assessment of cancer risk of microplastics enriched with polycyclic aromatic hydrocarbons[J]. Journal of Hazardous Materials, 2020, 398:122994 Khalid N, Aqeel M, Noman A, et al. Interactions and effects of microplastics with heavy metals in aquatic and terrestrial environments[J]. Environmental Pollution, 2021, 290:118104 Cheng Y, Lu J, Fu S, et al. Enhanced propagation of intracellular and extracellular antibiotic resistance genes in municipal wastewater by microplastics[J]. Environmental Pollution, 2022, 292:118284 Amato-Lourenço L F, de Souza Xavier Costa N, Dantas K C, et al. Airborne microplastics and SARS-CoV-2 in total suspended particles in the area surrounding the largest medical centre in Latin America[J]. Environmental Pollution, 2022, 292(Pt A):118299 -
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